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Picrotin

PubChem CID: 442291

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Compound Synonyms picrotin, 21416-53-5, Picrotin (VAN), CHEBI:8205, U06Z6QD7N2, PICROTIN [MI], DSSTox_CID_25605, DSSTox_RID_80998, UNII-U06Z6QD7N2, DSSTox_GSID_45605, CHEMBL478523, DTXSID80274161, NSC 129536, NSC-129536, (1R,3R,5S,8S,9R,12S,13R,14S)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione, 3,6-Methano-8H-1,5,7-trioxacyclopenta(ij)cycloprop(a)azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR-(1a alpha,2a beta,3beta,6beta,6a beta,8aS*,8b beta,9S*))-, Picrotin (from Anamirta cocculus seed), BRN 5302552, CAS-124-87-8, AI3-41570, (1R,3R,5S,8S,9R,12S,13R,14S)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo[6.4.1.1(9,12).0(3,5).0(5,13)]tetradecane-6,11-dione, 3,6-Methano-8H-1,5,7-trioxacyclopenta(ij)cycloprop(a)azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-, Pikrotin, NCGC00017246-02, (1R,3R,5S,8S,9R,12S,13R,14S)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo(6.4.1.1(9,12).0(3,5).0(5,13))tetradecane-6,11-dione, (1R,3R,5S,8S,9R,12S,13R,14S)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo(6.4.1.19,12.03,5.05,13)tetradecane-6,11-dione, (1S,3S,5R,9S,12R,13S,14R)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo(6.4.1.19,12.03,5.05,13)tetradecane-6,11-dione, (1S,3S,5R,9S,12R,13S,14R)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione, 3,6-Methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-, MFCD00868514, Spectrum_000413, ST057242, Spectrum2_000279, Spectrum3_000073, Spectrum4_001781, Spectrum5_000421, Picrotin (VAN) (8CI), BSPBio_001885, KBioGR_002323, KBioSS_000893, SPECTRUM100346, DivK1c_000756, SPBio_000158, GTPL4286, SCHEMBL1688919, HMS502F18, KBio1_000756, KBio2_000893, KBio2_003461, KBio2_006029, KBio3_001105, DTXCID50196568, NINDS_000756, HMS1922N10, Tox21_110806, Tox21_111261, BDBM50269961, CCG-39837, AKOS024282616, FP66559, SDCCGMLS-0066351.P001, IDI1_000756, SMP1_000239, NCGC00017246-10, NCGC00142523-02, NCGC00142523-04, (5S,8S,12S,14S,1R,3R,9R,13R)-1-hydroxy-14-(1-hydroxy-isopropyl)-13-methyl-4,7, 10-trioxapentacyclo[6.4.1.1<9,12>.0<3,5>.0<5,13>]tetradecane-6,11-dione, MS-24507, NS00096985, C09528, G12776, Q27088386
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 106.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CC2CC1C1CC3CC34C(C)CC2C14
Np Classifier Class Picrotoxane sesquiterpenoids
Deep Smiles O=CO[C@@H][C@H][C@H]5[C@]O)C[C@@H][C@][C@@]5[C@@H]9OC5=O))))C))O3))))))CO)C)C
Heavy Atom Count 22.0
Classyfire Class Furopyrans
Scaffold Graph Node Level OC1OC2CC1C1CC3OC34C(O)OC2C14
Isotope Atom Count 0.0
Molecular Complexity 644.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name (1R,3R,5S,8S,9R,12S,13R,14S)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp -0.8
Gsk 4 400 Rule True
Molecular Formula C15H18O7
Scaffold Graph Node Bond Level O=C1OC2CC1C1CC3OC34C(=O)OC2C14
Inchi Key RYEFFICCPKWYML-QCGISDTRSA-N
Silicos It Class Soluble
Rotatable Bond Count 1.0
Synonyms picrotin
Esol Class Very soluble
Functional Groups CC(=O)OC, CO, C[C@H]1O[C@@]12CCOC2=O
Compound Name Picrotin
Exact Mass 310.105
Formal Charge 0.0
Monoisotopic Mass 310.105
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 310.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C15H18O7/c1-12(2,18)6-7-10(16)20-8(6)9-13(3)14(7,19)4-5-15(13,22-5)11(17)21-9/h5-9,18-19H,4H2,1-3H3/t5-,6+,7-,8-,9-,13-,14-,15+/m1/s1
Smiles C[C@@]12[C@H]3[C@H]4[C@H]([C@@H]([C@@]1(C[C@@H]5[C@]2(O5)C(=O)O3)O)C(=O)O4)C(C)(C)O
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Sesquiterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Anamirta Cocculus (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279