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5-Methoxy-N-[(5-Methylpyridin-2-Yl)sulfonyl]-1h-Indole-2-Carboxamide

PubChem CID: 44229000

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Compound Synonyms CHEMBL1232723, 5-Methoxy-N-[(5-Methylpyridin-2-Yl)sulfonyl]-1h-Indole-2-Carboxamide, 3iub, BDBM50400277, Q27460281, FG2
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 110.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC(CC(C)(C)C1CCCCC1)C1CC2CCCCC2C1
Np Classifier Class Carboline alkaloids
Deep Smiles COcccccc6)cc[nH]5)C=O)NS=O)=O)cccccn6))C
Heavy Atom Count 24.0
Classyfire Class Indoles and derivatives
Scaffold Graph Node Level OC(NS(O)(O)C1CCCCN1)C1CC2CCCCC2N1
Classyfire Subclass Indolecarboxylic acids and derivatives
Isotope Atom Count 0.0
Molecular Complexity 562.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 5-methoxy-N-(5-methylpyridin-2-yl)sulfonyl-1H-indole-2-carboxamide
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.4
Gsk 4 400 Rule True
Molecular Formula C16H15N3O4S
Scaffold Graph Node Bond Level O=C(NS(=O)(=O)c1ccccn1)c1cc2ccccc2[nH]1
Inchi Key ZKUFSBNJBIOKLO-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 4.0
Synonyms fg2
Esol Class Soluble
Functional Groups cC(=O)NS(c)(=O)=O, cOC, c[nH]c, cnc
Compound Name 5-Methoxy-N-[(5-Methylpyridin-2-Yl)sulfonyl]-1h-Indole-2-Carboxamide
Exact Mass 345.078
Formal Charge 0.0
Monoisotopic Mass 345.078
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 345.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C16H15N3O4S/c1-10-3-6-15(17-9-10)24(21,22)19-16(20)14-8-11-7-12(23-2)4-5-13(11)18-14/h3-9,18H,1-2H3,(H,19,20)
Smiles CC1=CN=C(C=C1)S(=O)(=O)NC(=O)C2=CC3=C(N2)C=CC(=C3)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids