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Grosheimin

PubChem CID: 442256

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Compound Synonyms Grosheimin, Grosshemin, Grossheimin, 22489-66-3, UNII-ML3SLU81RH, ML3SLU81RH, NSC 295425, CHEBI:5547, NSC-295425, (3aR,4S,6aR,9S,9aR,9bR)-4-hydroxy-9-methyl-3,6-dimethylidene-3a,4,5,6a,7,9,9a,9b-octahydroazuleno[4,5-b]furan-2,8-dione, Azuleno[4,5-b]furan-2,8(3H,4H)-dione, octahydro-4-hydroxy-9-methyl-3,6-bis(methylene)-, (3aR,4S,6aR,9S,9aR,9bR)-, 4-beta-H-Guaia-10(14),11(13)-dien-12-oic acid, 6-alpha,8-alpha-dihydroxy-3-oxo-, 12,6-lactone, AZULENO(4,5-B)FURAN-2,8(3H,4H)-DIONE, OCTAHYDRO-4-HYDROXY-9-METHYL-3,6-BIS(METHYLENE)-, (3AR,4S,6AR,9S,9AR,9BR)-, Azuleno(4,5-b)furan-2,8(3H,4H)-dione, octahydro-4-hydroxy-9-methyl-3,6-bis(methylene)-, (3aR-(3aalpha,4alpha,6aalpha,9alpha,9aalpha,9bbeta))-, Groshemin, MLS001164143, CHEMBL271958, SCHEMBL1711489, GTPL12468, DTXSID60945165, HMS2864F18, HY-N10412, DA-50916, SMR000539503, CS-0527771, NS00094010, C09472, BRD-K20815397-001-03-7, Q27106805, 4.BETA.H-GUAIA-10(14),11(13)-DIEN-12-OIC ACID, 6.ALPHA.,8.ALPHA.-DIHYDROXY-3-OXO-, 12,6-LACTONE, 4betaH-GUAIA-10(14),11(13)-DIEN-12-OIC ACID, 6alpha,8alpha-DIHYDROXY-3-OXO-, 12,6-LACTONE, Azuleno[4,5-b]furan-2,8(3H,4H)-dione,octahydro-4-hydroxy-9-methyl-3,6-bis(methylene)-, (3aR,4S,6aR,9S,9aR,9bR)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 63.6
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2C(C)CCC3C(C)C(C)CC3C2C1
Np Classifier Class Guaiane sesquiterpenoids
Deep Smiles C[C@@H]C=O)C[C@@H][C@H]5[C@H]OC=O)C=C)[C@@H]5[C@H]CC%10=C)))O
Heavy Atom Count 19.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level CC1CCC2C(C)C(O)OC2C2CC(O)CC12
Classyfire Subclass Terpene lactones
Isotope Atom Count 0.0
Molecular Complexity 492.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 6.0
Uniprot Id n.a., P51450, Q962Y6, P00811, Q9UNA4, Q8IUX4, O75496, Q99700, P43220, Q9NUW8, O75874
Iupac Name (3aR,4S,6aR,9S,9aR,9bR)-4-hydroxy-9-methyl-3,6-dimethylidene-3a,4,5,6a,7,9,9a,9b-octahydroazuleno[4,5-b]furan-2,8-dione
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 0.8
Gsk 4 400 Rule True
Molecular Formula C15H18O4
Scaffold Graph Node Bond Level C=C1CCC2C(=C)C(=O)OC2C2CC(=O)CC12
Prediction Swissadme 0.0
Inchi Key YGMIBVIKXJJQQJ-MSOSQAFRSA-N
Silicos It Class Soluble
Fcsp3 0.6
Logs -1.993
Rotatable Bond Count 0.0
Logd 1.062
Synonyms grosheimin, grossheimin, grosshemin
Esol Class Very soluble
Functional Groups C=C(C)C, C=C1CCOC1=O, CC(C)=O, CO
Compound Name Grosheimin
Prediction Hob Swissadme 0.0
Exact Mass 262.121
Formal Charge 0.0
Monoisotopic Mass 262.121
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 262.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -1.9891909999999997
Inchi InChI=1S/C15H18O4/c1-6-4-11(17)13-8(3)15(18)19-14(13)12-7(2)10(16)5-9(6)12/h7,9,11-14,17H,1,3-5H2,2H3/t7-,9+,11+,12+,13-,14-/m1/s1
Smiles C[C@H]1[C@H]2[C@@H](CC1=O)C(=C)C[C@@H]([C@@H]3[C@@H]2OC(=O)C3=C)O
Nring 3.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Sesquiterpenoids

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  • 2. Outgoing r'ship FOUND_IN to/from Centaurea Behen (Plant) Rel Props:Reference:ISBN:9788185042114
  • 3. Outgoing r'ship FOUND_IN to/from Cynara Scolymus (Plant) Rel Props:Source_db:npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Grevillea Robusta (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Merendera Sobolifera (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Psorothamnus Spinosus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Sapindus Rarak (Plant) Rel Props:Source_db:npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Trachelospermum Asiaticum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Youngia Japonica (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/19571418