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Erysotrine

PubChem CID: 442219

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Compound Synonyms Erysotrine, 27740-43-8, (+)-Erysotrine, (2R,13bS)-2,11,12-trimethoxy-2,6,8,9-tetrahydro-1H-indolo[7a,1-a]isoquinoline, CHEBI:4838, Erythrinan, 1,2,6,7-tetradehydro-3,15,16-trimethoxy-, (3beta)-, Erysotrin, C09423, 57JE7XNE7L, CHEMBL442947, DTXSID80182090, HY-N3852, BDBM50006648, AKOS032948694, FS-9705, DA-52993, CS-0024334, NS00094798, Q27106501, (3beta)-1,2,6,7-Tetradehydro-3,15,16-trimethoxyerythrinan, (9bS,11R)-7,8,11-trimethoxy-2H,4H,5H,10H,11H-indolo[7a,1-a]isoquinoline, (1S,16R)-4,5,16-trimethoxy-10-azatetracyclo[8.7.0.0^{1,13}.0^{2,7}]heptadeca-2(7),3,5,12,14-pentaene
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 30.9
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCC1CCC3CCCCC312
Np Classifier Class Indolizidine alkaloids
Deep Smiles CO[C@H]C=CC=CCN[C@]5C9)cccOC))ccc6CC%10))))OC
Heavy Atom Count 23.0
Classyfire Class Erythrina alkaloids
Scaffold Graph Node Level C1CCC2C(C1)CCN1CCC3CCCCC321
Classyfire Subclass Erythrinanes
Isotope Atom Count 0.0
Molecular Complexity 517.0
Database Name cmaup_ingredients;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 2.0
Uniprot Id P43681
Iupac Name (2R,13bS)-2,11,12-trimethoxy-2,6,8,9-tetrahydro-1H-indolo[7a,1-a]isoquinoline
Prediction Hob 1.0
Class Erythrina alkaloids
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.1
Superclass Alkaloids and derivatives
Subclass Erythrinanes
Gsk 4 400 Rule True
Molecular Formula C19H23NO3
Scaffold Graph Node Bond Level C1=CC2=CCN3CCc4ccccc4C23CC1
Prediction Swissadme 1.0
Inchi Key WXVSPYOOFCCEII-KXBFYZLASA-N
Silicos It Class Soluble
Fcsp3 0.4736842105263157
Logs -3.126
Rotatable Bond Count 3.0
State Solid
Logd 2.339
Synonyms (+)-erysotrine, erysotrine
Esol Class Soluble
Functional Groups CC=C(C)C=CC, CN(C)C, COC, cOC
Compound Name Erysotrine
Kingdom Organic compounds
Prediction Hob Swissadme 1.0
Exact Mass 313.168
Formal Charge 0.0
Monoisotopic Mass 313.168
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 313.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -3.12630487826087
Inchi InChI=1S/C19H23NO3/c1-21-15-5-4-14-7-9-20-8-6-13-10-17(22-2)18(23-3)11-16(13)19(14,20)12-15/h4-5,7,10-11,15H,6,8-9,12H2,1-3H3/t15-,19-/m0/s1
Smiles CO[C@@H]1C[C@@]23C(=CCN2CCC4=CC(=C(C=C34)OC)OC)C=C1
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Erythrinanes
Np Classifier Superclass Lysine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Berberis Zycium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Cocculus Laurifolius (Plant) Rel Props:Reference:ISBN:9788172362133
  • 3. Outgoing r'ship FOUND_IN to/from Erythrina Arborescens (Plant) Rel Props:Reference:ISBN:9788172362300; ISBN:9788185042114
  • 4. Outgoing r'ship FOUND_IN to/from Erythrina Fusca (Plant) Rel Props:Reference:ISBN:9788185042084
  • 5. Outgoing r'ship FOUND_IN to/from Erythrina Glauca (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Erythrina Suberosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Erythrina Subumbrans (Plant) Rel Props:Reference:ISBN:9770972795006
  • 8. Outgoing r'ship FOUND_IN to/from Erythrina Variegata (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788172362300; ISBN:9788185042114