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(4R,7aR,12bS)-7-methoxy-1,2,3,4,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-9-ol

PubChem CID: 44221865

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Compound Synonyms SCHEMBL16487931
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 50.7
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CCCC45C(CCCC34)CC(C1)C25
Np Classifier Class Isoquinoline alkaloids, Morphinan alkaloids
Deep Smiles COC=CC=C[C@][C@H]6Occ5cC[C@H]9NCC%11)))))ccc6O
Heavy Atom Count 21.0
Classyfire Class Morphinans
Scaffold Graph Node Level C1CC2CC3NCCC45C(CCCC34)OC(C1)C25
Isotope Atom Count 0.0
Molecular Complexity 542.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name (4R,7aR,12bS)-7-methoxy-1,2,3,4,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-9-ol
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.4
Gsk 4 400 Rule True
Molecular Formula C17H17NO3
Scaffold Graph Node Bond Level C1=CC2Oc3cccc4c3C23CCNC(C4)C3=C1
Inchi Key FRLKJAAPFJROFZ-NVGVWMPQSA-N
Silicos It Class Soluble
Rotatable Bond Count 1.0
Synonyms oripavidine
Esol Class Soluble
Functional Groups CNC, COC1=CC=C(C)CC1, cO, cOC
Compound Name (4R,7aR,12bS)-7-methoxy-1,2,3,4,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-9-ol
Exact Mass 283.121
Formal Charge 0.0
Monoisotopic Mass 283.121
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 283.32
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C17H17NO3/c1-20-13-5-3-10-11-8-9-2-4-12(19)15-14(9)17(10,6-7-18-11)16(13)21-15/h2-5,11,16,18-19H,6-8H2,1H3/t11-,16+,17+/m1/s1
Smiles COC1=CC=C2[C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)O)CCN3
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Papaver Orientale (Plant) Rel Props:Reference:ISBN:9788185042084