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Aknadicine

PubChem CID: 442156

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Compound Synonyms Aknadicine, C09325, 24148-89-8, (1S,10S)-3-hydroxy-4,11,12-trimethoxy-17-azatetracyclo[8.4.3.01,10.02,7]heptadeca-2(7),3,5,11-tetraen-13-one, AC1L9CCN, DTXSID10331751, (1S,10S)-3-hydroxy-4,11,12-trimethoxy-17-azatetracyclo(8.4.3.01,10.02,7)heptadeca-2(7),3,5,11-tetraen-13-one, CHEBI:2529, DTXCID90964248, Q27105707
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 77.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC23CCCC2(C1)C1CCCCC1CC3
Np Classifier Class Hasubanan alkaloids, Isoquinoline alkaloids
Deep Smiles COC=COC))[C@][C@]CC6=O)))CCN5)))ccCC6))cccc6O))OC
Heavy Atom Count 25.0
Classyfire Class Hasubanan alkaloids
Scaffold Graph Node Level OC1CCC23CCC4CCCCC4C2(CCN3)C1
Isotope Atom Count 0.0
Molecular Complexity 605.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name (1S,10S)-3-hydroxy-4,11,12-trimethoxy-17-azatetracyclo[8.4.3.01,10.02,7]heptadeca-2(7),3,5,11-tetraen-13-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.3
Gsk 4 400 Rule True
Molecular Formula C19H23NO5
Scaffold Graph Node Bond Level O=C1C=CC23CCc4ccccc4C2(CCN3)C1
Prediction Swissadme 1.0
Inchi Key KTRLYLXLXTXHPM-RBUKOAKNSA-N
Silicos It Class Moderately soluble
Fcsp3 0.5263157894736842
Logs -2.167
Rotatable Bond Count 3.0
Logd 1.344
Synonyms aknadicine
Esol Class Soluble
Functional Groups CNC, COC(C)=C(OC)C(C)=O, cO, cOC
Compound Name Aknadicine
Prediction Hob Swissadme 1.0
Exact Mass 345.158
Formal Charge 0.0
Monoisotopic Mass 345.158
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 345.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.761149
Inchi InChI=1S/C19H23NO5/c1-23-13-5-4-11-6-7-19-17(25-3)16(24-2)12(21)10-18(19,8-9-20-19)14(11)15(13)22/h4-5,20,22H,6-10H2,1-3H3/t18-,19+/m0/s1
Smiles COC1=C(C2=C(CC[C@@]34[C@@]2(CCN3)CC(=O)C(=C4OC)OC)C=C1)O
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Stephania Hernandifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Stephania Japonica (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279