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Trichotomine

PubChem CID: 442120

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Compound Synonyms Trichotomine, 53472-14-3, 52GDN97EHY, UNII-52GDN97EHY, C09247, (5S)-2-[(5S)-5-carboxy-3-hydroxy-6,11-dihydro-5H-indolizino[8,7-b]indol-2-yl]-3-oxo-5,6-dihydroindolizino[8,7-b]indole-5-carboxylic acid, (2E,5S)-2-((5S)-5-Carboxy-6,11-dihydro-3-oxo-3H-indolizino(8,7-b)indol-2(5H)-ylidene)-2,5,6,11-tetrahydro-3-oxo-3H-indolizino(8,7-b)indole-5-carboxylic acid, 3H-Indolizino(8,7-b)indole-5-carboxylic acid, 2-((5S)-5-carboxy-6,11-dihydro-3-oxo-3H-indolizino(8,7-b)indol-2(5H)-ylidene)-2,5,6,11-tetrahydro-3-oxo-, (2E,5S)-, 3H-Indolizino(8,7-b)indole-5-carboxylic acid, 2-(5-carboxy-6,11-dihydro-3-oxo-3H-indolizino(8,7-b)indol-2(5H)-ylidene)-2,5,6,11-tetrahydro-3-oxo-, (S-(R*,R*-(E)))-, AC1NQYFB, (2E,5S)-2-[(5S)-5-carboxy-3-oxo-6,11-dihydro-5H-indolizino[8,7-b]indol-2-ylidene]-3-oxo-6,11-dihydro-5H-indolizino[8,7-b]indole-5-carboxylic acid, CHEBI:9693, DTXSID00415115, EX-A6299, Q7841058
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 148.0
Hydrogen Bond Donor Count 4.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1C(C2CC3CCC4C5CCCCC5CC4C3C2)CC2C1CCC1C3CCCCC3CC12
Np Classifier Class Carboline alkaloids
Deep Smiles OC=O)[C@@H]CC=cccccc6=NC9=CN%13C=O)C=C5)ccc-c[nH]ccc5C[C@H]n9c%12O)))C=O)O)))))cccc6
Heavy Atom Count 40.0
Classyfire Class Indoles and derivatives
Scaffold Graph Node Level OC1C(C2CC3C4NC5CCCCC5C4CCN3C2)CC2C3NC4CCCCC4C3CCN12
Classyfire Subclass Pyridoindoles
Isotope Atom Count 0.0
Molecular Complexity 1440.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name (5S)-2-[(5S)-5-carboxy-3-hydroxy-6,11-dihydro-5H-indolizino[8,7-b]indol-2-yl]-3-oxo-5,6-dihydroindolizino[8,7-b]indole-5-carboxylic acid
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.3
Gsk 4 400 Rule False
Molecular Formula C30H20N4O6
Scaffold Graph Node Bond Level O=C1C(c2cc3n(c2)CCc2c-3[nH]c3ccccc23)=CC2=C3N=c4ccccc4=C3CCN12
Inchi Key LGVWLGJCDLVSOA-ZEQRLZLVSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms trichotomine
Esol Class Moderately soluble
Functional Groups CC(=O)O, cC1=CC(=C(C)N=c)N(C)C1=O, cO, c[nH]c, cn(c)C
Compound Name Trichotomine
Exact Mass 532.138
Formal Charge 0.0
Monoisotopic Mass 532.138
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 532.5
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C30H20N4O6/c35-27-17(11-21-25-15(9-23(29(37)38)33(21)27)13-5-1-3-7-19(13)31-25)18-12-22-26-16(14-6-2-4-8-20(14)32-26)10-24(30(39)40)34(22)28(18)36/h1-8,11-12,23-24,31,35H,9-10H2,(H,37,38)(H,39,40)/t23-,24-/m0/s1
Smiles C1[C@H](N2C(=CC(=C2O)C3=CC4=C5C(=C6C=CC=CC6=N5)C[C@H](N4C3=O)C(=O)O)C7=C1C8=CC=CC=C8N7)C(=O)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Tryptophan alkaloids