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Tetrahydroharmine

PubChem CID: 442118

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Compound Synonyms (R)-Tetrahydroharmine, (+)-Tetrahydroharmine, AF812R7053, 7759-46-8, UNII-AF812R7053, 1H-Pyrido(3,4-b)indole, 2,3,4,9-tetrahydro-7-methoxy-1-methyl-, (+)-, 1H-Pyrido(3,4-b)indole, 2,3,4,9-tetrahydro-7-methoxy-1-methyl-, (R)-, 1H-Pyrido(3,4-b)indole, 2,3,4,9-tetrahydro-7-methoxy-1-methyl-, (1R)-, (1R)-7-methoxy-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole, C09243, 1,2,3,4-Tetrahydroharmine, UNII-F1Q1E0G45A, AC1L9CA2, (1r)-tetrahydroharmine, CHEBI:9485, SCHEMBL22800099, DTXSID201027156, NS00094370, Q27895793
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 37.1
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CCCCC12
Np Classifier Class Carboline alkaloids
Deep Smiles COcccccc6)[nH]cc5CCN[C@@H]6C
Heavy Atom Count 16.0
Classyfire Class Harmala alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1CNCCC12
Isotope Atom Count 0.0
Molecular Complexity 258.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name (1R)-7-methoxy-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.9
Gsk 4 400 Rule True
Molecular Formula C13H16N2O
Scaffold Graph Node Bond Level c1ccc2c3c([nH]c2c1)CNCC3
Prediction Swissadme 1.0
Inchi Key ZXLDQJLIBNPEFJ-MRVPVSSYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.3846153846153846
Logs -1.401
Rotatable Bond Count 1.0
Logd 1.815
Synonyms tetrahydroharmine
Esol Class Soluble
Functional Groups CNC, cOC, c[nH]c
Compound Name Tetrahydroharmine
Prediction Hob Swissadme 1.0
Exact Mass 216.126
Formal Charge 0.0
Monoisotopic Mass 216.126
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 216.28
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.7030108000000004
Inchi InChI=1S/C13H16N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,7-8,14-15H,5-6H2,1-2H3/t8-/m1/s1
Smiles C[C@@H]1C2=C(CCN1)C3=C(N2)C=C(C=C3)OC
Nring 3.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Glycyrrhiza Uralensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Peganum Harmala (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Tribulus Terrestris (Plant) Rel Props:Reference:ISBN:9788171360536