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Palmarin

PubChem CID: 442068

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Compound Synonyms Palmarin, Tinosporide, Arcangelisin, Isochasmanthin, Palmarine, 17226-41-4, (1S,2S,3S,5R,8S,11R,12S,13S,15S)-5-(furan-3-yl)-12-hydroxy-3,11-dimethyl-6,14,16-trioxapentacyclo[10.3.2.02,11.03,8.013,15]heptadecane-7,17-dione, 4-Hydroxy-2,3-15,16-diepoxycleroda-13(16),14-dieno-17,12-18-1-biscarbolactone, (1S,2S,3S,5R,8S,11R,12S,13S,15S)-5-(furan-3-yl)-12-hydroxy-3,11-dimethyl-6,14,16-trioxapentacyclo(10.3.2.02,11.03,8.013,15)heptadecane-7,17-dione, C09151, CHEBI:7894, DTXSID80938110, Q27107608, 2-(Furan-3-yl)-7-hydroxy-6a,9b-dimethyldodecahydro-4H-9,7-(epoxymethano)oxireno[6,7]naphtho[2,1-c]pyran-4,11-dione, 9,7-(Epoxymethano)-4H-oxireno(6,7)naphtho(2,1-c)pyran-4,11-dione, 2-(3-furanyl)dodecahydro-7-hydroxy-6a,9b-dimethyl-, (2S-(2alpha,4aalpha,6abeta,7beta,7abeta,8abeta,9alpha,9abeta,9balpha))-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 98.5
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CC(C2CCCC2)CC2C1CCC1C3C(C)CC(C4CC43)C21
Np Classifier Class Colensane and Clerodane diterpenoids
Deep Smiles O=CO[C@H]C[C@@][C@@H]6CC[C@@][C@H]6[C@@H]OC=O)[C@@]6O)[C@@H][C@H]6O3))))))))C)))))C)))ccocc5
Heavy Atom Count 27.0
Classyfire Class Naphthopyrans
Scaffold Graph Node Level OC1OC(C2CCOC2)CC2C1CCC1C3C(O)OC(C4OC43)C21
Isotope Atom Count 0.0
Molecular Complexity 738.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 9.0
Iupac Name (1S,2S,3S,5R,8S,11R,12S,13S,15S)-5-(furan-3-yl)-12-hydroxy-3,11-dimethyl-6,14,16-trioxapentacyclo[10.3.2.02,11.03,8.013,15]heptadecane-7,17-dione
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 1.3
Gsk 4 400 Rule True
Molecular Formula C20H22O7
Scaffold Graph Node Bond Level O=C1OC(c2ccoc2)CC2C1CCC1C3C(=O)OC(C4OC43)C21
Prediction Swissadme 1.0
Inchi Key TXOMRNMZLZXJQP-ZQTGRHRJSA-N
Silicos It Class Soluble
Fcsp3 0.7
Logs -4.241
Rotatable Bond Count 1.0
Logd 2.423
Synonyms palmarin, tinosporide, tinosporine
Esol Class Soluble
Functional Groups CC(=O)OC, CO, COC(C)=O, C[C@H]1O[C@H]1C, coc
Compound Name Palmarin
Prediction Hob Swissadme 1.0
Exact Mass 374.137
Formal Charge 0.0
Monoisotopic Mass 374.137
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 374.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.0701488370370376
Inchi InChI=1S/C20H22O7/c1-18-7-11(9-4-6-24-8-9)25-16(21)10(18)3-5-19(2)14(18)12-13-15(26-13)20(19,23)17(22)27-12/h4,6,8,10-15,23H,3,5,7H2,1-2H3/t10-,11-,12-,13+,14+,15+,18-,19-,20+/m1/s1
Smiles C[C@@]12CC[C@@H]3C(=O)O[C@H](C[C@]3([C@@H]1[C@H]4[C@H]5[C@@H]([C@@]2(C(=O)O4)O)O5)C)C6=COC=C6
Nring 7.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Diterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Corydalis Incisa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Jateorhiza Palmata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Tinospora Capillipes (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Tinospora Sinensis (Plant) Rel Props:Reference:ISBN:9788171360536; ISBN:9788172363130; ISBN:9788185042053; ISBN:9788185042114; ISBN:9788185042145