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Auricularine

PubChem CID: 441990

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Compound Synonyms Auricularine, 73706-32-8, C09043, N,N-dimethyl-2-[2-[(1S,9R,10S,15R,16R)-12,14,14,19-tetramethyl-8,19-diazapentacyclo[7.7.3.01,9.02,7.010,15]nonadeca-2,4,6,11-tetraen-16-yl]-1H-indol-3-yl]ethanamine, AC1L9C25, CHEBI:2927, CHEMBL4165417, DTXSID40331704, Q27105884
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 34.3
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2CC(C3C4CCCCC4C45CCCC34C3CCCCC3C5)CC2C1
Np Classifier Class Carboline alkaloids
Deep Smiles CNCCccccccc6[nH]c9[C@@H][C@@H][C@@H][C@][C@]5CCN5C))))cccccc6N9)))))))))C=CCC6C)C)))C)))))))))))))))))C
Heavy Atom Count 37.0
Classyfire Class Indoles and derivatives
Scaffold Graph Node Level C1CCC2NC(C3C4CCCCC4C45NCCC34C3CCCCC3N5)CC2C1
Classyfire Subclass Pyrroloindoles
Isotope Atom Count 0.0
Molecular Complexity 925.0
Database Name imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name N,N-dimethyl-2-[2-[(1S,9R,10S,15R,16R)-12,14,14,19-tetramethyl-8,19-diazapentacyclo[7.7.3.01,9.02,7.010,15]nonadeca-2,4,6,11-tetraen-16-yl]-1H-indol-3-yl]ethanamine
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 6.2
Gsk 4 400 Rule False
Molecular Formula C33H42N4
Scaffold Graph Node Bond Level C1=CC2C(CC1)C(c1cc3ccccc3[nH]1)C13CCNC21Nc1ccccc13
Inchi Key RTHNIWHULJBNTJ-BXFVMDGOSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 4.0
Synonyms auricularine
Esol Class Poorly soluble
Functional Groups CC(C)=CC, CN(C)C, cN[C@](C)(C)N(C)C, c[nH]c
Compound Name Auricularine
Exact Mass 494.341
Formal Charge 0.0
Monoisotopic Mass 494.341
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 494.7
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C33H42N4/c1-21-19-25-28(31(2,3)20-21)29(30-23(15-17-36(4)5)22-11-7-9-13-26(22)34-30)32-16-18-37(6)33(25,32)35-27-14-10-8-12-24(27)32/h7-14,19,25,28-29,34-35H,15-18,20H2,1-6H3/t25-,28-,29-,32+,33+/m0/s1
Smiles CC1=C[C@H]2[C@@H]([C@H]([C@]34[C@]2(NC5=CC=CC=C53)N(CC4)C)C6=C(C7=CC=CC=C7N6)CCN(C)C)C(C1)(C)C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Tryptophan alkaloids