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Adifoline

PubChem CID: 441972

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Compound Synonyms Adifoline, 20072-28-0, DTXSID30331697, C09020, (14S,18S,19S,20R)-5,18-dihydroxy-15-methoxycarbonyl-20-methyl-17-oxa-1,11-diazapentacyclo[10.8.1.02,7.08,21.014,19]henicosa-2(7),3,5,8,10,12(21),15-heptaene-10-carboxylic acid, AC1L9C18, (14S,18S,19S,20R)-5,18-dihydroxy-15-methoxycarbonyl-20-methyl-17-oxa-1,11-diazapentacyclo(10.8.1.02,7.08,21.014,19)henicosa-2(7),3,5,8,10,12(21),15-heptaene-10-carboxylic acid, CHEBI:2488, DTXCID30282791, AK-693/21087001, Q27105684
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 131.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule True
Scaffold Graph Level C1CCC2CC3C4CCCCC4C4CCCC(CC2C1)C43
Np Classifier Class Corynanthe type
Deep Smiles COC=O)C=CO[C@@H][C@H][C@@H]6Ccncccc6n[C@@H]%11C))cc5cccc6))O)))))))))C=O)O))))))))O
Heavy Atom Count 31.0
Classyfire Class Akageran and related alkaloids
Scaffold Graph Node Level C1CCC2C(C1)C1CCNC3CC4CCOCC4CN2C31
Isotope Atom Count 0.0
Molecular Complexity 788.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name (14S,18S,19S,20R)-5,18-dihydroxy-15-methoxycarbonyl-20-methyl-17-oxa-1,11-diazapentacyclo[10.8.1.02,7.08,21.014,19]henicosa-2(7),3,5,8,10,12(21),15-heptaene-10-carboxylic acid
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.9
Gsk 4 400 Rule False
Molecular Formula C22H20N2O7
Scaffold Graph Node Bond Level C1=CC2Cc3nccc4c5ccccc5n(c34)CC2CO1
Inchi Key DJWXVEDJWPDUBQ-DEALGVFLSA-N
Silicos It Class Soluble
Rotatable Bond Count 3.0
Synonyms adifoline
Esol Class Soluble
Functional Groups COC(=O)C1=CO[C@H](O)CC1, cC(=O)O, cO, cn(c)C, cnc
Compound Name Adifoline
Exact Mass 424.127
Formal Charge 0.0
Monoisotopic Mass 424.127
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 424.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H20N2O7/c1-9-18-12(14(21(28)30-2)8-31-22(18)29)6-15-19-13(7-16(23-15)20(26)27)11-5-10(25)3-4-17(11)24(9)19/h3-5,7-9,12,18,22,25,29H,6H2,1-2H3,(H,26,27)/t9-,12-,18-,22+/m1/s1
Smiles C[C@@H]1[C@@H]2[C@H](CC3=C4N1C5=C(C4=CC(=N3)C(=O)O)C=C(C=C5)O)C(=CO[C@@H]2O)C(=O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Haldina Cordifolia (Plant) Rel Props:Reference:ISBN:9788172361792