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Cymarine

PubChem CID: 441853

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Compound Synonyms CYMARIN, 508-77-0, K-Strophanthin-alpha, Cymarine, Stropheantin K, Strofantidina cimaroside, Strophanthidin-D-cymarosid, Cymarin (VAN), UNII-UK3LS8435E, Alvonal MR, WV 90043a, Strofantidina cimaroside [Italian], NSC 7522, Strophanthidin-D-cymarosid [German], EINECS 208-087-9, BRN 0101370, CHEBI:4037, UK3LS8435E, CYMARIN [MI], CYMARIN [MART.], CYMARIN [WHO-DD], 5-18-05-00129 (Beilstein Handbook Reference), Cimarin, MEGxp0_001730, CHEMBL1075788, Strophanthidin 3-O-beta-D-cymaroside, 5-beta-Card-20(22)-enolide, 3-beta-(beta-D-cymarosyloxy)-5,14-dihydroxy-19-oxo-, Card-20(22)-enolide, 3-((2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)-, k-Strophanthin-.alpha., CYMARIN (MART.), Strophantin K, Tsimarin, Zimarin, h Strophanthin, h-Strophanthin, NSC-7522, (3S,5S,8R,9S,10S,13R,14S,17R)-5,14-dihydroxy-3-[(2R,4S,5R,6R)-5-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl]oxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde, 3.BETA.-((2,6-DIDEOXY-3-O-METHYL-.BETA.-D-RIBO-HEXOPYRANOSYL)OXY)-5,14-DIHYDROXY-19-OXO-5.BETA.,14.BETA.-CARD-20(22)-ENOLIDE, k Strophanthin alpha, (3S,5S,8R,9S,10S,13R,14S,17R)-5,14-dihydroxy-3-[(2R,4S,5R,6R)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde, AC1L9BRZ, (3S,5S,8R,9S,10S,13R,14S,17R)-5,14-dihydroxy-3-((2R,4S,5R,6R)-5-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl)oxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthrene-10-carbaldehyde, B 652272K044, Cymarin (VAN) (8CI), SCHEMBL641739, Cymarin, >=96% (HPLC), STOCK1N-53317, ACon0_000820, ACon1_001275, DTXSID20871714, 5.beta.,17.alpha.-Card-20(22)enolide, 3.beta.,5,14-trihydroxy-19-oxo-, 3-cymaroside, 5.beta.-Card-20(22)-enolide, 3.beta.-(.beta.-D-cymarosyloxy)-5,14-dihydroxy-19-oxo-, XQCGNURMLWFQJR-ZNDDOCHDSA-N, 3.beta.-[(2,6-Dideoxy-3-O-methyl-.beta.-d-ribopyranosyl)oxy]-5.beta.,14-dihydroxy-19-oxocard-20(22)-enolide, BDBM50255121, MFCD00003669, AKOS030503859, DB13240, SMP1_000086, NCGC00169509-01, NCGC00169509-02, DA-62603, FC156960, HY-111934, CS-0094132, C08859, AO-774/41465371, Q5199357, BRD-K08486545-001-01-8, 5beta,17alpha-Card-20(22)enolide, 3beta,5,14-trihydroxy-19-oxo-, 3-cymaroside, 5beta-Card-20(22)-enolide, 3beta-(beta-D-cymarosyloxy)-5,14-dihydroxy-19-oxo-, (3S,5S,9S,10S,13R,14S,17R)-5,14-dihydroxy-3-((2R,4S,5R,6R)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yloxy)-13-methyl-17-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde, 208-087-9, 3BETA-((2,6-DIDEOXY-3-O-METHYL-BETA-D-RIBO-HEXOPYRANOSYL)OXY)-5,14-DIHYDROXY-19-OXO-5BETA,14BETA-CARD-20(22)-ENOLIDE, 3beta-((2,6-Dideoxy-3-O-methyl-beta-d-ribopyranosyl)oxy)-5beta,14-dihydroxy-19-oxocard-20(22)-enolide
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 132.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC(C2CCC3C2CCC2C4CCC(CC5CCCCC5)CC4CCC23)C1
Np Classifier Class Cardenolides
Deep Smiles CO[C@H]C[C@H]O[C@H]CC[C@][C@]C6)O)CC[C@@H][C@@H]6CC[C@][C@]6O)CC[C@@H]5C=CC=O)OC5)))))))))C)))))))))C=O)))))))O[C@@H][C@H]6O))C
Heavy Atom Count 39.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level OC1CC(C2CCC3C2CCC2C4CCC(OC5CCCCO5)CC4CCC23)CO1
Classyfire Subclass Steroid lactones
Isotope Atom Count 0.0
Molecular Complexity 1030.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 12.0
Uniprot Id P07340
Iupac Name (3S,5S,8R,9S,10S,13R,14S,17R)-5,14-dihydroxy-3-[(2R,4S,5R,6R)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 0.8
Gsk 4 400 Rule False
Molecular Formula C30H44O9
Scaffold Graph Node Bond Level O=C1C=C(C2CCC3C2CCC2C4CCC(OC5CCCCO5)CC4CCC23)CO1
Prediction Swissadme 0.0
Inchi Key XQCGNURMLWFQJR-ZNDDOCHDSA-N
Silicos It Class Soluble
Fcsp3 0.8666666666666667
Logs -3.618
Rotatable Bond Count 5.0
Logd 1.806
Synonyms cymarin
Esol Class Soluble
Functional Groups CC1=CC(=O)OC1, CC=O, CO, COC, C[C@H](OC)OC
Compound Name Cymarine
Prediction Hob Swissadme 0.0
Exact Mass 548.299
Formal Charge 0.0
Monoisotopic Mass 548.299
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 548.7
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 12.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.3149726000000026
Inchi InChI=1S/C30H44O9/c1-17-26(33)23(36-3)13-25(38-17)39-19-4-9-28(16-31)21-5-8-27(2)20(18-12-24(32)37-15-18)7-11-30(27,35)22(21)6-10-29(28,34)14-19/h12,16-17,19-23,25-26,33-35H,4-11,13-15H2,1-3H3/t17-,19+,20-,21+,22-,23+,25+,26-,27-,28+,29+,30+/m1/s1
Smiles C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2CC[C@@]3([C@H]4CC[C@@]5([C@H](CC[C@@]5([C@@H]4CC[C@@]3(C2)O)O)C6=CC(=O)OC6)C)C=O)OC)O
Nring 6.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Steroids

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