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Conessine

PubChem CID: 441082

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Compound Synonyms conessine, 546-06-5, Roquessine, Neriine, Conessin, Wrightine, Conessinum, Conesina, Conessine [INN], NSC 119994, Conesina [INN-Spanish], Conessinum [INN-Latin], EZ38J9BBDF, Konessin, 3beta-(Dimethylamino)con-5-ene, DTXSID6046000, CHEBI:27965, CONESSINE [MI], EINECS 208-897-2, N,N-dimethylcon-5-enin-3beta-amine, MFCD00016752, NSC-119994, BRN 4702160, (3-beta)-N,N-Dimethylcon-5-enin-3-amine, DTXCID4026000, 3beta-(Dimethylamino)con-5-enine, Conkurchine, N,18-dihydrotrimethyl-, Con-5-enine, 3beta-(dimethylamino)-, Conesina (INN-Spanish), Conessinum (INN-Latin), Con-5-enin-3-amine, N,N-dimethyl-, (3beta)-, (1R,2S,5S,6S,9R,12S,13R,16S)-N,N,6,7,13-pentamethyl-7-azapentacyclo[10.8.0.02,9.05,9.013,18]icos-18-en-16-amine, Con-5-enine, 3.beta.-(dimethylamino)-, UNII-EZ38J9BBDF, NCGC00095844-01, (1R,2S,5S,6S,9R,12S,13R,16S)-N,N,6,7,13-pentamethyl-7-azapentacyclo(10.8.0.02,9.05,9.013,18)icos-18-en-16-amine, CAS-546-06-5, (+)-Conessine, Prestwick_692, ST066907, Prestwick0_000638, Prestwick1_000638, Prestwick2_000638, Prestwick3_000638, ConessineWrightine, Conessine, BSPBio_000636, BIDD:ER0525, SCHEMBL791146, SPBio_002855, BPBio1_000700, CHEMBL191703, GTPL8981, Conessine, >=97% (HPLC), BDBM27193, GLXC-26648, HMS1569P18, HMS2096P18, 3 beta-(dimethylamino)con-5-enine, Tox21_111531, MSK164242, AKOS024283367, Tox21_111531_1, FC57645, NCGC00092388-01, NCGC00092388-03, NCGC00092388-05, NCGC00092388-15, ((2S,5S,12S,16S,1R,9R,13R)-6,7,13-trimethyl-7-azapentacyclo[10.8.0.0<2,9>.0<5, 9>.0<13,18>]icos-18-en-16-yl)dimethylamine, MS-25590, (3beta)-N,N-dimethyl-con-5-enin-3-amine, Conkurchine, N,18-dihydrotrimethyl-(7CI), HY-107566, Con-5-enine, 3beta-(dimethylamino)-(8CI), NS00033145, C06545, F82154, A1-00780, Q5159518, Con-5-enin-3-amine, N,N-dimethyl-, (3beta)-(9CI), (1R,2S,5S,6S,9R,12S,13R,16S)-N,N,6,7,13-pentamethyl-7-azapentacyclo[10.8.0.0^{2,9}.0^{5,9}.0^{13,18}]icos-18-en-16-amine, 208-897-2
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 6.5
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCC1C2CCC23CCCC2CCC13
Np Classifier Class Steroidal alkaloids
Deep Smiles CN[C@H]CC[C@]C=CC[C@@H][C@@H]6CC[C@@][C@H]6CC[C@@H]5[C@@H]NC8)C))C)))))))))))))C6))C)))))C
Heavy Atom Count 26.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level C1CCC2C(C1)CCC1C2CCC23CNCC2CCC13
Classyfire Subclass Steroidal alkaloids
Isotope Atom Count 0.0
Molecular Complexity 609.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 8.0
Uniprot Id n.a., Q9QYN8, Q9Y5N1, P18825, P35367, P25021, Q9H3N8, P08913, Q9JI35, P28593, P16473, P97697, P16050, P15917, O42275, P81908, Q9NUW8, Q9Y6L6, Q9NPD5, P27695, Q51487, P10275, P19838
Iupac Name (1R,2S,5S,6S,9R,12S,13R,16S)-N,N,6,7,13-pentamethyl-7-azapentacyclo[10.8.0.02,9.05,9.013,18]icos-18-en-16-amine
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Target Id NPT987, NPT224, NPT222, NPT210, NPT792
Xlogp 4.9
Gsk 4 400 Rule False
Molecular Formula C24H40N2
Scaffold Graph Node Bond Level C1=C2CCCCC2C2CCC34CNCC3CCC4C2C1
Prediction Swissadme 0.0
Inchi Key GPLGAQQQNWMVMM-MYAJQUOBSA-N
Silicos It Class Moderately soluble
Fcsp3 0.9166666666666666
Logs -4.396
Rotatable Bond Count 1.0
Logd 4.119
Synonyms conessine
Esol Class Moderately soluble
Functional Groups CC=C(C)C, CN(C)C
Compound Name Conessine
Prediction Hob Swissadme 0.0
Exact Mass 356.319
Formal Charge 0.0
Monoisotopic Mass 356.319
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 356.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.0529068
Inchi InChI=1S/C24H40N2/c1-16-20-8-9-22-19-7-6-17-14-18(25(3)4)10-12-23(17,2)21(19)11-13-24(20,22)15-26(16)5/h6,16,18-22H,7-15H2,1-5H3/t16-,18-,19+,20+,21-,22-,23-,24-/m0/s1
Smiles C[C@H]1[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3CC=C5[C@@]4(CC[C@@H](C5)N(C)C)C)CN1C
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids, Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Pseudoalkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Alpinia Formosana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Anisocycla Grandidieri (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Asparagus Setaceus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Bambusa Tulda (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Bidens Parviflora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Croton Balsamifer (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Diplospora Dubia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Elsholtzia Stauntonii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Flindersia Australis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Funtumia Elastica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Haemanthus Tigrinus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Heliotropium Angiospermum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 13. Outgoing r'ship FOUND_IN to/from Holarrhena Mitis (Plant) Rel Props:Reference:ISBN:9788185042084
  • 14. Outgoing r'ship FOUND_IN to/from Holarrhena Pubescens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 15. Outgoing r'ship FOUND_IN to/from Leucas Volkensii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 16. Outgoing r'ship FOUND_IN to/from Mentha Suaveolens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 17. Outgoing r'ship FOUND_IN to/from Papaver Hybrid (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 18. Outgoing r'ship FOUND_IN to/from Pinus Bungeana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 19. Outgoing r'ship FOUND_IN to/from Piper Hostmannianum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 20. Outgoing r'ship FOUND_IN to/from Prostanthera Prunelloides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 21. Outgoing r'ship FOUND_IN to/from Protea Compacta (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 22. Outgoing r'ship FOUND_IN to/from Rubus Moluccanus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 23. Outgoing r'ship FOUND_IN to/from Typhonium Flagelliforme (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 24. Outgoing r'ship FOUND_IN to/from Vincetoxicum Stauntonii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 25. Outgoing r'ship FOUND_IN to/from Wrightia Arborea (Plant) Rel Props:Reference:ISBN:9788172361150; ISBN:9788185042084