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3-Hydroxybutyric acid

PubChem CID: 441

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Compound Synonyms 3-hydroxybutyric acid, 3-hydroxybutanoic acid, 300-85-6, Butanoic acid, 3-hydroxy-, 625-71-8, DL-3-Hydroxybutyric Acid, beta-Hydroxybutyric acid, 3 HBA, 3-Hydroxybuttersaeure, Butyric acid, 3-hydroxy-, DL-beta-Hydroxybutyric acid, beta-Hydroxybuttersaeure, 26063-00-3, beta-Hydroxy-n-butyric acid, poly(3-hydroxybutyric acid), 3 Hydroxybutyrate, 3-hydroxy-butanoic acid, .beta.-Hydroxybutyric acid, (1)-3-Hydroxybutyric acid, (+-)-3-Hydroxybutyric acid, beta-hydroxy-butyrate, D,l-3 hydroxybutyrate, beta-hydroxybutanoic acid, NSC 3806, NSC-3806, Hydroxybutyric acid, dl-, MFCD00004546, .beta.-Hydroxy-n-butyric acid, AI3-21675, (+/-)-3-Hydroxybutyric Acid, D(-)-beta-hydroxy butyric acid, CHEBI:20067, 3-hydroxybutyric acid, (+/-)-, TZP1275679, 3-hydroxy-butyrate, Butyric acid, 3-hydroxy- (8CI), 3-Hydroxybutanoic Acid + 3-(3-Hydroxybutyryloxy)butyric Acid (CAS:7565-79-9) (50:50 Mixture), SMR000112209, (+/-)-3-Hydroxybutyric Acid (Technical Grade), MFCD00137685, UNII-TZP1275679, EINECS 206-099-9, EINECS 210-908-0, 3-OH-butyric acid, BHBA, 3- hydroxybutyric acid, 3-hydroxy-butyric acid, DL-3-HydroxybutyricAcid, d,l-3-hydroxybutyric acid, bmse000161, bmse000905, SCHEMBL2731, (RS)-3-hydroxybutyric acid, (+/-)-beta-Hydroxybutyrate, MLS001332397, MLS001332398, 3-Hydroxybutyric acid, 95%, DL-.beta.-Hydroxybutyric acid, (+/-)-3-Hydroxybutanoic acid, CHEMBL1162496, .BETA.HYDROXYBUTYRIC ACID, DTXSID60859511, NSC3806, (.+/-.)-3-Hydroxybutyric acid, 3-Hydroxybutyric acid, tech grade, HMS2270C20, HMS3369F13, BBL027467, HB4640, LMFA01050005, s1031, STL377875, AKOS009156821, AB88579, AC-5701, FH30882, SB44475, Butanoic acid, 3-hydroxy-, (+/-)-, .BETA.-HYDROXYBUTYRIC ACID [MI], Butanoic acid, 3-hydroxy-, (A+/-)-, BETA-HYDROXYBUTYRIC ACID [WHO-DD], FP179872, SY074781, SY076545, SY114480, VS-08544, HY-113378, CS-0062335, H0228, NS00014717, Poly(3-hydroxybutyric acid), MW~500,000, D84191, EN300-147463, Poly[(R)-3-hydroxybutyrate], Mn ~500,000, Q223092, BRD-A41387824-001-06-0, (+/-)-3-Hydroxybutanoic acid, DL-?-Hydroxybutyric acid, 869DD3C9-3114-4BE2-B4A6-6F1787476E95
Topological Polar Surface Area 57.5
Hydrogen Bond Donor Count 2.0
Heavy Atom Count 7.0
Description 3-Hydroxybutanoic acid is a ketone body. It is a chiral compound having two enantiomers. The concentration of beta-hydroxybutyrate, like that of other ketone bodies, is increased in ketosis. In humans, beta-hydroxybutyrate is synthesized in the liver from acetyl-CoA in a reaction catalyzed by the enzyme beta-hydroxybutyrate dehydrogenase and can be used as an energy source by the brain when blood glucose is low. Diabetic patients can have their ketone levels tested via urine or blood to indicate diabetic ketoacidosis. In alcoholic ketoacidosis, this ketone body is produced in greatest concentration. Both types of ketoacidosis result in an increasebeta-hydroxybutyrate to oxaloacetate ratio, resulting in TCA cycle stalling and shifting of glucose towards ketone body production. [Wikipedia]
Isotope Atom Count 0.0
Molecular Complexity 69.3
Database Name cmaup_ingredients;fooddb_chem_all;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id Q8VC69, Q80UJ1, P53987, O60669, Q66HS9, P34707, n.a., P0DTD1
Iupac Name 3-hydroxybutanoic acid
Prediction Hob 1.0
Class Fatty Acyls
Xlogp -0.5
Superclass Lipids and lipid-like molecules
Subclass Fatty acids and conjugates
Molecular Formula C4H8O3
Prediction Swissadme 0.0
Inchi Key WHBMMWSBFZVSSR-UHFFFAOYSA-N
Fcsp3 0.75
Logs 0.701
Rotatable Bond Count 2.0
State Solid
Logd -1.282
Synonyms (1)-3-Hydroxybutyrate, (1)-3-Hydroxybutyric acid, 3 HBA, 3-Hydroxy-butanoate, 3-Hydroxy-butanoic acid, 3-Hydroxy-butyrate, 3-Hydroxy-butyric acid, 3-Hydroxybutanoate, 3-Hydroxybuttersaeure, 3-Hydroxybutyrate, 3-Hydroxybutyric acid, 3-OH-Butyrate, 3-OH-Butyric acid, b-Hydroxy-N-butyrate, b-Hydroxy-N-butyric acid, b-Hydroxybutanoate, b-Hydroxybutanoic acid, b-Hydroxybuttersaeure, b-Hydroxybutyrate, b-Hydroxybutyric acid, beta-Hydroxy-N-butyrate, beta-Hydroxy-N-butyric acid, beta-Hydroxybutanoate, beta-Hydroxybutanoic acid, beta-Hydroxybuttersaeure, beta-Hydroxybutyrate, beta-Hydroxybutyric acid, BHBA, Biopol, DL-3-Hydroxybutyrate, DL-3-Hydroxybutyric acid, DL-b-Hydroxybutyrate, DL-b-Hydroxybutyric acid, DL-beta-Hydroxybutyrate, DL-beta-Hydroxybutyric acid, DL-β-hydroxybutyrate, DL-β-hydroxybutyric acid, β-hydroxy-N-butyrate, β-hydroxy-N-butyric acid, β-hydroxybutanoate, β-hydroxybutanoic acid, β-hydroxybuttersaeure, β-hydroxybutyrate, β-hydroxybutyric acid
Substituent Name Hydroxy fatty acid, Short-chain hydroxy acid, Beta-hydroxy acid, Hydroxy acid, Secondary alcohol, Monocarboxylic acid or derivatives, Carboxylic acid, Carboxylic acid derivative, Hydrocarbon derivative, Organooxygen compound, Carbonyl group, Alcohol, Aliphatic acyclic compound
Compound Name 3-Hydroxybutyric acid
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 104.047
Formal Charge 0.0
Monoisotopic Mass 104.047
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 104.1
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Esol -0.019550999999999763
Inchi InChI=1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)
Smiles CC(CC(=O)O)O
Nring 0.0
Defined Bond Stereocenter Count 0.0

  • 1. Outgoing r'ship FOUND_IN to/from Aloe Africana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Aloe Barbadensis (Plant) Rel Props:Source_db:npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Aloe Ferox (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Aloe Spicata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Aloe Vera (Plant) Rel Props:Source_db:cmaup_ingredients