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Macarpine

PubChem CID: 440929

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Compound Synonyms Macarpine, 23594-80-1, CHEBI:17101, 11,15-dimethoxy-24-methyl-5,7,18,20-tetraoxa-24-azoniahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(13),2,4(8),9,11,14,16,21,23-nonaene, 5,7-dimethoxy-13-methyl-2H,10H-[1,3]dioxolo[4,5-i][1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridinium, [1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium, 5,7-dimethoxy-13-methyl-, 11,15-dimethoxy-24-methyl-5,7,18,20-tetraoxa-24-azoniahexacyclo(11.11.0.02,10.04,8.014,22.017,21)tetracosa-1(13),2,4(8),9,11,14,16,21,23-nonaene, 5,7-dimethoxy-13-methyl-2H,10H-(1,3)dioxolo(4,5-i)(1,3)dioxolo(4',5':4,5)benzo(1,2-c)phenanthridinium, C06165, CHEMBL5205934, DTXSID20946395, Q3841952, 5,7-Dimethoxy-13-methyl-2H,10H-[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, 6917-73-3
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 59.3
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CCC4C(CCC5C6CCCC6CCC54)C3CC2C1
Np Classifier Class Isoquinoline alkaloids
Deep Smiles COcccccOC))cccc6c[n+]c%10cc%14ccOCOc5c9))))))))))C))))OCO5
Heavy Atom Count 29.0
Classyfire Class Benzophenanthridine alkaloids
Scaffold Graph Node Level C1OC2CC3CCC4C5CCC6OCOC6C5CNC4C3CC2O1
Classyfire Subclass Quaternary benzophenanthridine alkaloids
Isotope Atom Count 0.0
Molecular Complexity 620.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 11,15-dimethoxy-24-methyl-5,7,18,20-tetraoxa-24-azoniahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(13),2,4(8),9,11,14,16,21,23-nonaene
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 4.4
Gsk 4 400 Rule True
Molecular Formula C22H18NO6+
Scaffold Graph Node Bond Level c1cc2c(c[nH+]c3c4cc5c(cc4ccc23)OCO5)c2c1OCO2
Prediction Swissadme 0.0
Inchi Key SBVRPBAVNZNLKX-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.2272727272727272
Logs -8.302
Rotatable Bond Count 2.0
Logd 3.514
Synonyms macarpine
Esol Class Moderately soluble
Functional Groups c1cOCO1, cOC, c[n+](c)C
Compound Name Macarpine
Prediction Hob Swissadme 0.0
Exact Mass 392.113
Formal Charge 1.0
Monoisotopic Mass 392.113
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 392.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.365809744827588
Inchi InChI=1S/C22H18NO6/c1-23-8-14-20(18(25-3)7-19-22(14)29-10-28-19)13-6-15(24-2)11-4-16-17(27-9-26-16)5-12(11)21(13)23/h4-8H,9-10H2,1-3H3/q+1
Smiles C[N+]1=CC2=C3C(=CC(=C2C4=C1C5=CC6=C(C=C5C(=C4)OC)OCO6)OC)OCO3
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Colysis Pothifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Eschscholzia Californica (Plant) Rel Props:Reference:ISBN:9788172362300
  • 3. Outgoing r'ship FOUND_IN to/from Garcinia Xanthochymus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Nicotiana Plumbaginifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Pueraria Tuberosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all