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(S)-Cheilanthifoline

PubChem CID: 440582

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Compound Synonyms (S)-Cheilanthifoline, 483-44-3, (13S)-17-methoxy-5,7-dioxa-1-azapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-16-ol, CHEBI:16233, (6aS)-6,6a,11,14-Tetrahydro-8-methoxy-12H-benzo[a]-1,3-benzodioxolo[4,5-g]quinolizim-9-ol, (6aS)-9-methoxy-6,11,12,14-tetrahydro-2H,6aH-[1,3]dioxolo[4,5-h]isoquino[2,1-b]isoquinolin-8-ol, (6aS)-6, 6a, 11,14-tetrahydro-8-methoxy-12H-benzo[a]-1,3-benzodioxolo[4, 5-g]quinolizim-9-ol, (13S)-17-methoxy-5,7-dioxa-1-azapentacyclo(11.8.0.03,11.04,8.014,19)henicosa-3(11),4(8),9,14,16,18-hexaen-16-ol, (6aS)-6, 6a, 11,14-tetrahydro-8-methoxy-12H-benzo(a)-1,3-benzodioxolo(4, 5-g)quinolizim-9-ol, (6AS)-6,6a,11,14-tetrahydro-8-methoxy-12H-benzo(a)-1,3-benzodioxolo(4,5-g)quinolizim-9-ol, (6aS)-9-methoxy-6,11,12,14-tetrahydro-2H,6aH-(1,3)dioxolo(4,5-h)isoquino(2,1-b)isoquinolin-8-ol, C05174, SCHEMBL18890976, DTXSID70964044, NS00093943, E87180, Q15410880, 9-Methoxy-6,11,12,14-tetrahydro-2H,6aH-[1,3]dioxolo[4,5-h]isoquinolino[2,1-b]isoquinolin-8-ol
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 51.2
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCC1CC3C(CCC4CCCC43)CC12
Np Classifier Class Isoquinoline alkaloids, Protoberberine alkaloids
Deep Smiles COcccCCN[C@H]c6cc%10O))))CccC6)cOCOc5cc9
Heavy Atom Count 24.0
Classyfire Class Protoberberine alkaloids and derivatives
Scaffold Graph Node Level C1CCC2C(C1)CCN1CC3C(CCC4OCOC43)CC21
Isotope Atom Count 0.0
Molecular Complexity 474.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name (13S)-17-methoxy-5,7-dioxa-1-azapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-16-ol
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.8
Gsk 4 400 Rule True
Molecular Formula C19H19NO4
Scaffold Graph Node Bond Level c1ccc2c(c1)CCN1Cc3c(ccc4c3OCO4)CC21
Inchi Key FVXCQULKSPVRPK-HNNXBMFYSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 1.0
Synonyms (-) cheilanthifoline, cheilanthifoline
Esol Class Soluble
Functional Groups CN(C)C, c1cOCO1, cO, cOC
Compound Name (S)-Cheilanthifoline
Exact Mass 325.131
Formal Charge 0.0
Monoisotopic Mass 325.131
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 325.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C19H19NO4/c1-22-18-7-12-4-5-20-9-14-11(2-3-17-19(14)24-10-23-17)6-15(20)13(12)8-16(18)21/h2-3,7-8,15,21H,4-6,9-10H2,1H3/t15-/m0/s1
Smiles COC1=C(C=C2[C@@H]3CC4=C(CN3CCC2=C1)C5=C(C=C4)OCO5)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

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