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Deacetoxyvindoline

PubChem CID: 439783

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Compound Synonyms Deacetoxyvindoline, Desacetoxyvindoline, CHEBI:16957, methyl (1R,9R,10R,12R,19S)-12-ethyl-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate, methyl (1R,9R,10R,12R,19S)-12-ethyl-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo(10.6.1.01,9.02,7.016,19)nonadeca-2(7),3,5,13-tetraene-10-carboxylate, DTXSID901032203, methyl 3beta-hydroxy-16-methoxy-1-methyl-6,7-didehydro-2beta,5alpha,12beta,19alpha-aspidospermidine-3alpha-carboxylate, C02673, 16-Methoxy-2,3-dihydro-3-hydroxy-N-methyltabersonine, Q19903943, 105119-60-6, Methyl 3b-hydroxy-16-methoxy-1-methyl-6,7-didehydro-2b,5a,12b,19a-aspidospermidine-3a-carboxylate, Methyl 3b-hydroxy-16-methoxy-1-methyl-6,7-didehydro-2b,5a,12b,19a-aspidospermidine-3a-carboxylic acid, Methyl 3beta-hydroxy-16-methoxy-1-methyl-6,7-didehydro-2beta,5alpha,12beta,19alpha-aspidospermidine-3alpha-carboxylic acid, Methyl 3I2-hydroxy-16-methoxy-1-methyl-6,7-didehydro-2I2,5I+-,12I2,19I+--aspidospermidine-3I+--carboxylate, Methyl 3I2-hydroxy-16-methoxy-1-methyl-6,7-didehydro-2I2,5I+-,12I2,19I+--aspidospermidine-3I+--carboxylic acid
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 62.2
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CCC3CCCC4CCC12C34
Np Classifier Class Aspidosperma type, Aspidosperma-Iboga hybrid type (Vinca alkaloids)
Deep Smiles COcccccc6)NC)[C@@H][C@]5CCN[C@H]5[C@@]C[C@]9O)C=O)OC)))))CC))C=CC6
Heavy Atom Count 29.0
Classyfire Class Plumeran-type alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1CCC3CCCN4CCC12C34
Isotope Atom Count 0.0
Molecular Complexity 728.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name methyl (1R,9R,10R,12R,19S)-12-ethyl-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.8
Gsk 4 400 Rule True
Molecular Formula C23H30N2O4
Scaffold Graph Node Bond Level C1=CC2CCC3Nc4ccccc4C34CCN(C1)C24
Inchi Key WNKDGPXNFMMOEJ-RNJSZURPSA-N
Silicos It Class Soluble
Rotatable Bond Count 4.0
Synonyms 16-methoxy-2,3-dihydro-3-hydroxy-n-methyltabersonine, deacetoxyvindoline, desacetoxyvindoline
Esol Class Soluble
Functional Groups CC=CC, CN(C)C, CO, COC(C)=O, cN(C)C, cOC
Compound Name Deacetoxyvindoline
Exact Mass 398.221
Formal Charge 0.0
Monoisotopic Mass 398.221
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 398.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C23H30N2O4/c1-5-21-9-6-11-25-12-10-22(18(21)25)16-8-7-15(28-3)13-17(16)24(2)19(22)23(27,14-21)20(26)29-4/h6-9,13,18-19,27H,5,10-12,14H2,1-4H3/t18-,19+,21-,22+,23+/m0/s1
Smiles CC[C@]12C[C@@]([C@H]3[C@@]4([C@H]1N(CC4)CC=C2)C5=C(N3C)C=C(C=C5)OC)(C(=O)OC)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Reference:https://doi.org/10.1093/database/bav075