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Corynan-16-carboxylic acid, 16,17,19,20-tetradehydro-17-hydroxy-, methyl ester, (16E,19E)-

PubChem CID: 439666

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Compound Synonyms Corynan-16-carboxylic acid, 16,17,19,20-tetradehydro-17-hydroxy-, methyl ester, (16E,19E)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 62.4
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2C(CCC3C4CCCCC4CC23)C1
Np Classifier Class Corynanthe type
Deep Smiles COC=O)C[C@H]C[C@@H]NCC6=CC))))CCcc6[nH]cc5cccc6)))))))))))))))C=O
Heavy Atom Count 26.0
Classyfire Class Corynanthean-type alkaloids
Scaffold Graph Node Level CC1CCC2C3NC4CCCCC4C3CCN2C1
Isotope Atom Count 0.0
Molecular Complexity 590.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name methyl 2-[(2R,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-oxopropanoate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.2
Gsk 4 400 Rule True
Molecular Formula C21H24N2O3
Scaffold Graph Node Bond Level C=C1CCC2c3[nH]c4ccccc4c3CCN2C1
Inchi Key AUOFTPXWUVYOOQ-VBIIVCKISA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 4.0
Synonyms geissoschizine
Esol Class Soluble
Functional Groups CC=C(C)C, CC=O, CN(C)C, COC(C)=O, c[nH]c
Compound Name Corynan-16-carboxylic acid, 16,17,19,20-tetradehydro-17-hydroxy-, methyl ester, (16E,19E)-
Exact Mass 352.179
Formal Charge 0.0
Monoisotopic Mass 352.179
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 352.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H24N2O3/c1-3-13-11-23-9-8-15-14-6-4-5-7-18(14)22-20(15)19(23)10-16(13)17(12-24)21(25)26-2/h3-7,12,16-17,19,22H,8-11H2,1-2H3/t16-,17?,19-/m0/s1
Smiles CC=C1CN2CCC3=C([C@@H]2C[C@@H]1C(C=O)C(=O)OC)NC4=CC=CC=C34
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Reference:https://doi.org/10.1093/database/bav075
  • 2. Outgoing r'ship FOUND_IN to/from Rhazya Stricta (Plant) Rel Props:Reference:ISBN:9788185042145