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4-Ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione

PubChem CID: 4330531

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Compound Synonyms 10-Hydroxycamptothecin, 64439-81-2, (+/-)-10-Hydroxycamptothecin, 4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, ( inverted exclamation markA)-10-Hydroxycamptothecin, MFCD09027971, 19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione, 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4,9-dihydroxy-, (A+/-)-, Hydroxy camptothecine, 4-Ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, Neuro_000051, CHEMBL90124, 10-Hydroxycamptothecin acetate, SCHEMBL9384413, DTXSID501125515, BCP10548, HY-N0275, STL565783, (+/-)-10-HCPT, AKOS015901897, FH16009, AS-74592, SY311865, CS-0008775, (+/-)-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLINE-3,14(4H,12H)-DIONE, 19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0(2),(1)(1).0?,?.0(1)?,(2)?]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione, 4-Ethyl-4,9-dihydroxy-1H-pyrano[3a(2),4a(2):6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Topological Polar Surface Area 100.0
Hydrogen Bond Donor Count 2.0
Heavy Atom Count 27.0
Isotope Atom Count 0.0
Molecular Complexity 774.0
Database Name cmaup_ingredients;hmdb_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Prediction Hob 1.0
Class Camptothecins
Target Id NPT48, NPT93, NPT94
Xlogp 0.6
Superclass Alkaloids and derivatives
Molecular Formula C20H16N2O5
Prediction Swissadme 0.0
Inchi Key HAWSQZCWOQZXHI-UHFFFAOYSA-N
Fcsp3 0.25
Logs -4.345
Rotatable Bond Count 1.0
Logd 1.452
Synonyms 10-Hydroxycamptothecine
Compound Name 4-Ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 364.106
Formal Charge 0.0
Monoisotopic Mass 364.106
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 364.4
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Esol -3.9331319185185194
Inchi InChI=1S/C20H16N2O5/c1-2-20(26)14-7-16-17-11(5-10-6-12(23)3-4-15(10)21-17)8-22(16)18(24)13(14)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3
Smiles CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O
Nring 5.0
Defined Bond Stereocenter Count 0.0
Taxonomy Direct Parent Camptothecins