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methyl 2-(6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl)-3-methoxyprop-2-enoate

PubChem CID: 409518

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Compound Synonyms Rhynchophylline, Isorhyncophylline, 76-66-4, methyl 2-(6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl)-3-methoxyprop-2-enoate, Mitrinermin, 6859-01-4, METHYL 2-{6'-ETHYL-2-OXO-3',5',6',7',8',8'A-HEXAHYDRO-1H,2'H-SPIRO[INDOLE-3,1'-INDOLIZIN]-7'-YL}-3-METHOXYPROP-2-ENOATE, DTXSID30871548, Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid,6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-a-(methoxymethylene)-2-oxo-,methyl ester, (aE,1'R,6'R,7'S,8'aS)-, DB-050096, Methyl 17-methoxy-2-oxocorynox-16-en-16-carboxylate
Topological Polar Surface Area 67.9
Hydrogen Bond Donor Count 1.0
Heavy Atom Count 28.0
Isotope Atom Count 0.0
Molecular Complexity 663.0
Database Name cmaup_ingredients;hmdb_chem_all;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name methyl 2-(6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl)-3-methoxyprop-2-enoate
Prediction Hob 1.0
Class Indolizidines
Xlogp 2.3
Superclass Organoheterocyclic compounds
Molecular Formula C22H28N2O4
Prediction Swissadme 1.0
Inchi Key DAXYUDFNWXHGBE-UHFFFAOYSA-N
Fcsp3 0.5454545454545454
Logs -3.669
Rotatable Bond Count 5.0
Logd 3.219
Synonyms Methyl 2-{6'-ethyl-2-hydroxy-3',5',6',7',8',8'a-hexahydro-2'H-spiro[indole-3,1'-indolizine]-7'-yl}-3-methoxyprop-2-enoic acid, Isorhyncophylline, Rhyncophylline, Isorhynchophylline, Rhyncophylline, (16E)-isomer, Rhyncophylline, (16E,20alpha)-isomer
Compound Name methyl 2-(6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl)-3-methoxyprop-2-enoate
Kingdom Organic compounds
Prediction Hob Swissadme 1.0
Exact Mass 384.205
Formal Charge 0.0
Monoisotopic Mass 384.205
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 384.5
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 1.0
Molecular Framework Aromatic heteropolycyclic compounds
Esol -3.7092226285714296
Inchi InChI=1S/C22H28N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h5-8,13-15,19H,4,9-12H2,1-3H3,(H,23,26)
Smiles CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O
Nring 4.0
Defined Bond Stereocenter Count 0.0
Taxonomy Direct Parent Indolizidines

  • 1. Outgoing r'ship FOUND_IN to/from Uncaria Macrophylla (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Uncaria Rhynchophylla (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Uncaria Sinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all