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Phyllanthin

PubChem CID: 358901

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Compound Synonyms Phyllanthin, 10351-88-9, UNII-75O1TFF47Z, NSC-619043, 75O1TFF47Z, NSC619043, CHEBI:8177, 4-[(2S,3S)-3-[(3,4-dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl]-1,2-dimethoxybenzene, NSC 619043, NCI60_005684, Benzene, 1,1'-(2,3-bis(methoxymethyl)-1,4-butanediyl)bis(3,4-dimethoxy-, (S-(R*,R*))-, PHYLLANTHIN (USP-RS), PHYLLANTHIN [USP-RS], BUTANE, 1,4-DIMETHOXY-2,3-DIVERATRYL-, (2S,3S)-(+)-, BENZENE, 1,1'-((2S,3S)-2,3-BIS(METHOXYMETHYL)-1,4-BUTANEDIYL)BIS(3,4-DIMETHOXY-, AC1L7DK7, Phyllanthin (Standard), Phyllanthin, analytical standard, CHEMBL1253999, HY-N4107R, KFLQGJQSLUYUBF-WOJBJXKFSA-N, DTXSID001319088, HY-N4107, AKOS032948449, FP27032, DA-56827, MS-27324, CS-0032115, A1-06840, PHYLLANTHIN (CONSTITUENT OF PHYLLANTHUS AMARUS), Q27107847, PHYLLANTHIN (CONSTITUENT OF PHYLLANTHUS AMARUS) [DSC], Phyllanthin, United States Pharmacopeia (USP) Reference Standard, (6S,10R,11aR,11bS)-9,10,11,11a-Tetrahydro-10-methoxy-8H-6,11b-methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one, (4b)-4-Methoxysecurina n-11-one, (-)-Phyllanthine, 4-[(2S,3S)-3-[(3,4-dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl]-1,2-dimethoxy-benzene
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 55.4
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC(CCCCC2CCCCC2)CC1
Np Classifier Class Dibenzylbutane lignans
Deep Smiles COC[C@H][C@H]Ccccccc6)OC)))OC)))))))COC))))Ccccccc6)OC)))OC
Heavy Atom Count 30.0
Classyfire Class Dibenzylbutane lignans
Scaffold Graph Node Level C1CCC(CCCCC2CCCCC2)CC1
Isotope Atom Count 0.0
Molecular Complexity 407.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name 4-[(2S,3S)-3-[(3,4-dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl]-1,2-dimethoxybenzene
Veber Rule False
Classyfire Superclass Lignans, neolignans and related compounds
Xlogp 4.2
Gsk 4 400 Rule False
Molecular Formula C24H34O6
Scaffold Graph Node Bond Level c1ccc(CCCCc2ccccc2)cc1
Inchi Key KFLQGJQSLUYUBF-WOJBJXKFSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 13.0
Synonyms phyllanthin
Esol Class Moderately soluble
Functional Groups COC, cOC
Compound Name Phyllanthin
Exact Mass 418.236
Formal Charge 0.0
Monoisotopic Mass 418.236
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 418.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m1/s1
Smiles COC[C@@H](CC1=CC(=C(C=C1)OC)OC)[C@H](CC2=CC(=C(C=C2)OC)OC)COC
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Lignans

  • 1. Outgoing r'ship FOUND_IN to/from Phyllanthus Amarus (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/16236476
  • 2. Outgoing r'ship FOUND_IN to/from Phyllanthus Fraternus (Plant) Rel Props:Reference:ISBN:9788172360818; ISBN:9788172362461
  • 3. Outgoing r'ship FOUND_IN to/from Phyllanthus Niruri (Plant) Rel Props:Reference:ISBN:9788183602525