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Zingerone

PubChem CID: 31211

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Compound Synonyms ZINGERONE, Vanillylacetone, 122-48-5, 4-(4-Hydroxy-3-methoxyphenyl)butan-2-one, Zingherone, Zingiberone, 4-(4-Hydroxy-3-methoxyphenyl)-2-butanone, Gingerone, Vanillyl acetone, 2-Butanone, 4-(4-hydroxy-3-methoxyphenyl)-, 4-Hydroxy-3-methoxybenzylacetone, [0]-Paradol, (4-Hydroxy-3-methoxyphenyl)ethyl methyl ketone, (0)-Paradol, 3-Methoxy-4-hydroxybenzylacetone, 4-(3-Methoxy-4-hydroxyphenyl)-2-butanone, FEMA No. 3124, (O)-Paradol, 3-Methoxy-4-hydroxy-benzylacetone, 2-(4-Hydroxy-3-methoxyphenyl)ethyl methyl ketone, NSC 15335, vanillylaceton, CCRIS 2036, UNII-4MMW850892, HSDB 1064, EINECS 204-548-3, [0]Paradol, BRN 2051099, DTXSID8047420, CHEBI:68657, AI3-31837, Vanillylacetone, Gingerone, ZINGERONE [FCC], 4-(4-hydroxy-3-methoxy-phenyl)-butan-2-one, ZINGERONE [MI], ZINGERONE [FHFI], ZINGERONE [HSDB], MFCD00048232, NSC-15335, 4MMW850892, CHEMBL25894, VANILLYLACETON [WHO-DD], DTXCID6027420, FEMA 3124, 4-08-00-01866 (Beilstein Handbook Reference), (0)Paradol, 4-(3-methoxy-4-hydroxyphenyl)butan-2-one, 4-(4-Hydroxy-3-methoxyphenyl)-2-butanone, 9CI, 8CI, 0 paradol, Zincbacitracin, Zingerone (Standard), ZINGERONE [INCI], 3Methoxy4hydroxybenzylacetone, 4Hydroxy3methoxybenzylacetone, SCHEMBL119051, Vanillylacetone, >=96%, FG, 4-(4-hydroxy-3-methoxyphenyl)-, HMS3651E22, 4(3Methoxy4hydroxyphenyl)2butanone, 4(4Hydroxy3methoxyphenyl)2butanone, NSC15335, Tox21_302493, BDBM50304073, HY-14621R, s2371, STL564783, 2Butanone, 4(4hydroxy3methoxyphenyl), AKOS009462778, CCG-208511, DB15589, FV05929, Vanillylacetone, >=98%, natural, FG, Zingerone, analytical reference material, NCGC00256663-01, 1ST40217, AC-34331, AS-65368, CAS-122-48-5, HY-14621, SY017980, 4(4-Hydroxy-3-methoxyphenyl)-2-butanone, (4Hydroxy3methoxyphenyl)ethyl methyl ketone, DB-003808, 2(4Hydroxy3methoxyphenyl)ethyl methyl ketone, CS-0003480, H1314, NS00013332, SW219618-1, C17497, EN300-1721864, SR-05000013705, Q1064625, SR-05000013705-1, BRD-K33510429-001-02-3, BRD-K33510429-001-03-1, Z1255442373, 3-Methoxy-4-hydroxybenzylacetone, Zingerone, 4-(3-methoxy-4-hydroxyphenyl)-2-butanone
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 46.5
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCCCC1
Deep Smiles COcccCCC=O)C))))ccc6O
Heavy Atom Count 14.0
Classyfire Class Phenols
Description Reputed pungent principle of ginger (Zingiber officinale). Flavour material used in imitation fruit flavours, ginger beer, ginger ale etcand is also present in cranberry, raspberry and mango. Zingerone is found in many foods, some of which are pot marjoram, fruits, ginger, and herbs and spices.
Scaffold Graph Node Level C1CCCCC1
Classyfire Subclass Methoxyphenols
Isotope Atom Count 0.0
Molecular Complexity 191.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P22309, P0DMM9, n.a., O42713, P10275, O42275, P81908, Q13936
Iupac Name 4-(4-hydroxy-3-methoxyphenyl)butan-2-one
Prediction Hob 1.0
Class Benzene and substituted derivatives
Veber Rule True
Classyfire Superclass Benzenoids
Target Id NPT153, NPT2691
Xlogp 0.8
Superclass Benzenoids
Subclass Phenols and derivatives
Gsk 4 400 Rule True
Molecular Formula C11H14O3
Scaffold Graph Node Bond Level c1ccccc1
Prediction Swissadme 1.0
Inchi Key OJYLAHXKWMRDGS-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.3636363636363636
Logs -1.48
Rotatable Bond Count 4.0
State Solid
Logd 1.295
Synonyms (0)-Paradol, (4-Hydroxy-3-methoxyphenyl)ethyl methyl ketone, [0]-Paradol, [0]Paradol, 2-(4-Hydroxy-3-methoxyphenyl)ethyl methyl ketone, 2-Butanone, 4-(4-hydroxy-3-methoxyphenyl)-, 3-Methoxy-4-hydroxybenzylacetone, 4-(3-Methoxy-4-hydroxyphenyl)-2-butanone, 4-(3-Methoxy-4-hydroxyphenyl)butan-2-one, 4-(4-hydroxy-3-methoxy-phenyl)-butan-2-one, 4-(4-Hydroxy-3-methoxyphenyl)-2-butanone, 4-(4-Hydroxy-3-methoxyphenyl)-2-butanone, 9CI, 8CI, 4-(4-Hydroxy-3-methoxyphenyl)butan-2-one, 4-Hydroxy-3-methoxybenzylacetone, FEMA 3124, Gingerone, Vanillyl acetone, Vanillylacetone, Zingerone, Zingherone, Zingiberone, 0 Paradol, 4-(4-Hydroxy-3-methoxy-phenyl)-butan-2-one, 4-(4-Hydroxy-3-methoxyphenyl)-2-butanone, 9ci, 8ci, vanillylacetone, zingerone
Substituent Name Methoxyphenol, Methoxybenzene, Phenol ether, Anisole, Alkyl aryl ether, Ketone, Ether, Hydrocarbon derivative, Organooxygen compound, Carbonyl group, Aromatic homomonocyclic compound
Esol Class Very soluble
Functional Groups CC(C)=O, cO, cOC
Compound Name Zingerone
Kingdom Organic compounds
Prediction Hob Swissadme 1.0
Exact Mass 194.094
Formal Charge 0.0
Monoisotopic Mass 194.094
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 194.23
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic homomonocyclic compounds
Lipinski Rule Of 5 True
Esol -1.7966688571428573
Inchi InChI=1S/C11H14O3/c1-8(12)3-4-9-5-6-10(13)11(7-9)14-2/h5-7,13H,3-4H2,1-2H3
Smiles CC(=O)CCC1=CC(=C(C=C1)O)OC
Nring 1.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Methoxyphenols

  • 1. Outgoing r'ship FOUND_IN to/from Aframomum Melegueta (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.1554
  • 2. Outgoing r'ship FOUND_IN to/from Alpinia Officinarum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Myrica Esculenta (Plant) Rel Props:Reference:ISBN:9770972795006
  • 4. Outgoing r'ship FOUND_IN to/from Origanum Onites (Plant) Rel Props:Source_db:fooddb_chem_all;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Polyalthia Nemoralis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Vitis Vinifera (Plant) Rel Props:Reference:ISBN:9788172363093
  • 7. Outgoing r'ship FOUND_IN to/from Zingiber Officinale (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all