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GP 11

PubChem CID: 3086253

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Compound Synonyms GP 11, 87435-55-0, GP-11, 1-[[(5R,6R,8R)-8-hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxole-6-carbonyl]amino]-3-(2,2,5,5-tetramethyl-1-oxidopyrrol-3-yl)urea, N'-Podophyllic acid-N-(3-(2,2,5,5-tetramethylpyrrolinenyloxy))semicarbazide, DTXSID701007561, 3-{[Hydroxy(2-{hydroxy[8-hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydro-2H-naphtho[2,3-d][1,3]dioxol-6-yl]methylidene}hydrazinyl)methylidene]amino}-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-olate
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 183.0
Hydrogen Bond Donor Count 5.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC(CCC(C)C1CCC2CC3CCCC3CC2C1C1CCCCC1)CC1CCCC1
Deep Smiles OCC[C@H]C=O)NNC=O)NC=CCNC5C)C))[O-]))C)C)))))))))[C@H]cccOC))ccc6)OC)))OC))))))cc[C@@H]6O))cccc6)OCO5
Heavy Atom Count 45.0
Classyfire Class Aryltetralin lignans
Scaffold Graph Node Level OC(NNC(O)C1CCC2CC3OCOC3CC2C1C1CCCCC1)NC1CCNC1
Isotope Atom Count 0.0
Molecular Complexity 1110.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name 1-[[(5R,6R,8R)-8-hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxole-6-carbonyl]amino]-3-(2,2,5,5-tetramethyl-1-oxidopyrrol-3-yl)urea
Veber Rule False
Classyfire Superclass Lignans, neolignans and related compounds
Xlogp 1.5
Gsk 4 400 Rule False
Molecular Formula C31H39N4O10-
Scaffold Graph Node Bond Level O=C(NNC(=O)C1CCc2cc3c(cc2C1c1ccccc1)OCO3)NC1=CCNC1
Inchi Key ZDNKVESNZAJGCN-XZIDKQEJSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 7.0
Synonyms gp-11
Esol Class Moderately soluble
Functional Groups CC=C(C)NC(=O)NNC(C)=O, CN(C)[O-], CO, c1cOCO1, cOC
Compound Name GP 11
Exact Mass 627.267
Formal Charge -1.0
Monoisotopic Mass 627.267
Hydrogen Bond Acceptor Count 11.0
Molecular Weight 627.7
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 False
Inchi InChI=1S/C31H39N4O10/c1-30(2)12-23(31(3,4)35(30)40)32-29(39)34-33-28(38)25-18(13-36)26(37)17-11-20-19(44-14-45-20)10-16(17)24(25)15-8-21(41-5)27(43-7)22(9-15)42-6/h8-12,18,24-26,36-37H,13-14H2,1-7H3,(H,33,38)(H2,32,34,39)/q-1/t18?,24-,25+,26+/m1/s1
Smiles CC1(C=C(C(N1[O-])(C)C)NC(=O)NNC(=O)[C@@H]2[C@@H](C3=CC4=C(C=C3[C@@H](C2CO)O)OCO4)C5=CC(=C(C(=C5)OC)OC)OC)C
Defined Bond Stereocenter Count 0.0
Egan Rule False

  • 1. Outgoing r'ship FOUND_IN to/from Sinopodophyllum Hexandrum (Plant) Rel Props:Reference:https://doi.org/10.1093/database/bav075