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N-Methylnandigerine

PubChem CID: 3083908

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Compound Synonyms N-Methylnandigerine, 5544-68-3, Nandigerine, N-methyl derivative of, 18-methoxy-11-methyl-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,14(19),15,17-hexaen-17-ol, 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-11-ol, 6,7,7a,8-tetrahydro-12-methoxy-7-methyl-, (S)-, HMS2215P07, 18-methoxy-11-methyl-3,5-dioxa-11-azapentacyclo(10.7.1.02,6.08,20.014,19)icosa-1(20),2(6),7,14(19),15,17-hexaen-17-ol, N-Me. Nandigerine, MLS000575005, CHEMBL3194830, DTXSID10970780, HMS3351N11, NCGC00247615-01, SMR000156301, AE-508/21135031, 12-Methoxy-7-methyl-6,7,7a,8-tetrahydro-2H,5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-11-ol
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 51.2
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CCCC3CC4CCCC4C2C13
Np Classifier Class Aporphine alkaloids, Isoquinoline alkaloids
Deep Smiles COccO)cccc6-ccOCOc5ccc9CC%13)NC)CC6
Heavy Atom Count 24.0
Classyfire Class Aporphines
Scaffold Graph Node Level C1CCC2C(C1)CC1NCCC3CC4OCOC4C2C31
Isotope Atom Count 0.0
Molecular Complexity 488.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P02545, B2RXH2, Q96KQ7, O95149, Q9UNA4, P80244, P43220, Q13526, O75874, O95398
Iupac Name 18-methoxy-11-methyl-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,14(19),15,17-hexaen-17-ol
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Target Id NPT483, NPT48
Xlogp 2.9
Gsk 4 400 Rule True
Molecular Formula C19H19NO4
Scaffold Graph Node Bond Level c1ccc2c(c1)CC1NCCc3cc4c(c-2c31)OCO4
Prediction Swissadme 1.0
Inchi Key WOIZHRXESCUSGM-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.3684210526315789
Logs -1.942
Rotatable Bond Count 1.0
Logd 2.651
Synonyms nandigerine, n-methyl
Esol Class Moderately soluble
Functional Groups CN(C)C, c1cOCO1, cO, cOC
Compound Name N-Methylnandigerine
Prediction Hob Swissadme 1.0
Exact Mass 325.131
Formal Charge 0.0
Monoisotopic Mass 325.131
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 325.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.000856800000001
Inchi InChI=1S/C19H19NO4/c1-20-6-5-11-8-14-19(24-9-23-14)17-15(11)12(20)7-10-3-4-13(21)18(22-2)16(10)17/h3-4,8,12,21H,5-7,9H2,1-2H3
Smiles CN1CCC2=CC3=C(C4=C2C1CC5=C4C(=C(C=C5)O)OC)OCO3
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Hernandia Guianensis (Plant) Rel Props:Reference:ISBN:9788185042053
  • 2. Outgoing r'ship FOUND_IN to/from Hernandia Nymphaeifolia (Plant) Rel Props:Reference:ISBN:9788185042053
  • 3. Outgoing r'ship FOUND_IN to/from Lindera Megaphylla (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all