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Isocorynoxeine

PubChem CID: 3037448

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Compound Synonyms Isocorynoxeine, 51014-29-0, 7-Isocorynoxeine, UNII-J18B596D11, methyl (E)-2-[(3S,6'R,7'S,8'aS)-6'-ethenyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate, J18B596D11, Methyl (E)-3-methoxy-2-((3S,6'R,7'S,8a'S)-2-oxo-6'-vinyl-2',3',6',7',8',8a'-hexahydro-5'H-spiro[indoline-3,1'-indolizin]-7'-yl)acrylate, CHEMBL481359, DTXSID701317164, HY-N0775, BDBM50531269, MFCD20527292, s9239, AKOS030526830, CCG-268432, CS-3806, NCGC00482763-01, AC-34915, DA-74548, MS-26272, 1ST159055, Q27281021, CORYNOXAN-16-CARBOXYLIC ACID, 16,17,18,19-TETRADEHYDRO-17-METHOXY-2-OXO-, METHYL ESTER, (16E,20.ALPHA.)-, CORYNOXAN-16-CARBOXYLIC ACID, 16,17,18,19-TETRADEHYDRO-17-METHOXY-2-OXO-, METHYL ESTER, (16E,20alpha)-, SPIRO(3H-INDOLE-3,1'(5'H)-INDOLIZINE)-7'-ACETIC ACID, 6'-ETHENYL-1,2,2',3',6',7',8',8'A-OCTAHYDRO-.ALPHA.-(METHOXYMETHYLENE)-2-OXO-, METHYL ESTER, (.ALPHA.E,1'S,6'R,7'S,8'AS)-, SPIRO(3H-INDOLE-3,1'(5'H)-INDOLIZINE)-7'-ACETIC ACID, 6'-ETHENYL-1,2,2',3',6',7',8',8'A-OCTAHYDRO-alpha-(METHOXYMETHYLENE)-2-OXO-, METHYL ESTER, (alphaE,1'S,6'R,7'S,8'AS)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 67.9
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCCCC2C12CCC1CCCCC12
Np Classifier Class Simple oxindole alkaloids
Deep Smiles CO/C=C[C@H]C[C@@H]NC[C@@H]6C=C))))CC[C@@]5C=O)Ncc5cccc6)))))))))))))))/C=O)OC
Heavy Atom Count 28.0
Classyfire Class Indolizidines
Scaffold Graph Node Level OC1NC2CCCCC2C12CCN1CCCCC12
Isotope Atom Count 0.0
Molecular Complexity 690.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 4.0
Uniprot Id P08908
Iupac Name methyl (E)-2-[(3S,6'R,7'S,8'aS)-6'-ethenyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.1
Gsk 4 400 Rule True
Molecular Formula C22H26N2O4
Scaffold Graph Node Bond Level O=C1Nc2ccccc2C12CCN1CCCCC12
Prediction Swissadme 1.0
Inchi Key MUVGVMUWMAGNSY-VKCGGMIFSA-N
Silicos It Class Moderately soluble
Fcsp3 0.4545454545454545
Logs -3.64
Rotatable Bond Count 5.0
Logd 2.583
Synonyms isocorynoxeine
Esol Class Soluble
Functional Groups C=CC, CN(C)C, CO/C=C(C)C(=O)OC, cNC(C)=O
Compound Name Isocorynoxeine
Prediction Hob Swissadme 1.0
Exact Mass 382.189
Formal Charge 0.0
Monoisotopic Mass 382.189
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 382.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Esol -3.5392234285714292
Inchi InChI=1S/C22H26N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h4-8,13-15,19H,1,9-12H2,2-3H3,(H,23,26)/b16-13+/t14-,15-,19-,22-/m0/s1
Smiles CO/C=C(\[C@H]1C[C@H]2[C@]3(CCN2C[C@@H]1C=C)C4=CC=CC=C4NC3=O)/C(=O)OC
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Capsicum Annuum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Cestrum Parqui (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Fleroya Stipulosa (Plant) Rel Props:Reference:ISBN:9770972795006
  • 4. Outgoing r'ship FOUND_IN to/from Monostroma Nitidum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Rumex Chalepensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Uncaria Macrophylla (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Uncaria Rhynchophylla (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Uncaria Sinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all