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Allithiamine

PubChem CID: 3037212

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Compound Synonyms Allithiamine, 554-44-9, Thiamin-allyl-disulfid, N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(Z)-5-hydroxy-3-(prop-2-enyldisulfanyl)pent-2-en-2-yl]formamide, UNII-83SWN21920, 83SWN21920, THIAMINE ALLYL DISULFIDE, N-(4-Amino-2-methyl-5-pyrimidinylmethyl)-N-(2-allyldithio-4-hydroxy-1-methyl-1-butenyl)formamid, Formamide, N-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(4-hydroxy-1-methyl-2-(2-propenyldithio)-1-butenyl)-, N-((4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL)-N-((1Z)-4-HYDROXY-1-METHYL-2-(PROP-2-EN-1-YLDISULFANYL)BUT-1-EN-1-YL)FORMAMIDE, N-((2E)-5-Hydroxy-3-(prop-2-en-1-yldisulphanyl)pent-2-en-2-yl)-N-((6-imino-2-methyl-1,6-dihydropyrimidin-5-yl)methyl)formamide, N-((4-amino-2-methylpyrimidin-5-yl)methyl)-N-((E)-5-hydroxy-3-(prop-2-enyldisulfanyl)pent-2-en-2-yl)formamide, N-[(2E)-5-Hydroxy-3-(prop-2-en-1-yldisulphanyl)pent-2-en-2-yl]-N-[(6-imino-2-methyl-1,6-dihydropyrimidin-5-yl)methyl]formamide, N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(E)-5-hydroxy-3-(prop-2-enyldisulfanyl)pent-2-en-2-yl]formamide, SCHEMBL163426, CHEBI:169524, N-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-N-(4-hydroxy-1-methyl-2-(2-propenyldithio)-1-butenyl)formamide, 9ci, N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-(2-propenyldithio)-1-butenyl]formamide, 9CI, Q4732877, N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(Z)-5-hydroxy-3-(prop-2-enyldisulanyl)pent-2-en-2-yl]ormamide
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 143.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level C1CCCCC1
Deep Smiles OCC/C=C/NCccncnc6N)))C))))))C=O)))C))/SSCC=C
Heavy Atom Count 23.0
Classyfire Class Diazines
Scaffold Graph Node Level C1CNCNC1
Classyfire Subclass Pyrimidines and pyrimidine derivatives
Isotope Atom Count 0.0
Molecular Complexity 420.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(Z)-5-hydroxy-3-(prop-2-enyldisulfanyl)pent-2-en-2-yl]formamide
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 0.9
Gsk 4 400 Rule True
Molecular Formula C15H22N4O2S2
Scaffold Graph Node Bond Level c1cncnc1
Prediction Swissadme 0.0
Inchi Key WNCAVNGLACHSRZ-KAMYIIQDSA-N
Silicos It Class Soluble
Fcsp3 0.4
Logs -5.674
Rotatable Bond Count 9.0
Logd 4.37
Synonyms allithiamine
Esol Class Soluble
Functional Groups C=CC, CO, CSS/C(C)=C(/C)N(C)C=O, cN, cnc
Compound Name Allithiamine
Prediction Hob Swissadme 0.0
Exact Mass 354.118
Formal Charge 0.0
Monoisotopic Mass 354.118
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 354.5
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Esol -2.83094967826087
Inchi InChI=1S/C15H22N4O2S2/c1-4-7-22-23-14(5-6-20)11(2)19(10-21)9-13-8-17-12(3)18-15(13)16/h4,8,10,20H,1,5-7,9H2,2-3H3,(H2,16,17,18)/b14-11-
Smiles CC1=NC=C(C(=N1)N)CN(C=O)/C(=C(/CCO)\SSCC=C)/C
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True

  • 1. Outgoing r'ship FOUND_IN to/from Allium Sativum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Allium Schoenoprasum (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 3. Outgoing r'ship FOUND_IN to/from Aniba Megaphylla (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Berberis Integerrima (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Elephantopus Angustifolius (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Herbertus Sakuraii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Isoplexis Sceptrum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Libocedrus Decurrens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Loranthus Parasiticus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Sarcocephalus Latifolius (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all