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RA VII

PubChem CID: 3034401

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Compound Synonyms RA VII, 86229-97-2, RA-VII, Methylether of TPC-A, UNII-HVM25O0351, HVM25O0351, 6-(3-Hydroxy-N,O-dimethyl-L-tyrosine)-5-(N-methyl-L-tyrosine)bouvardin, (1S,4R,7S,10S,13S,16S)-24-methoxy-10-[(4-methoxyphenyl)methyl]-4,7,9,13,15,29-hexamethyl-22-oxa-3,6,9,12,15,29-hexazatetracyclo[14.12.2.218,21.123,27]tritriaconta-18,20,23,25,27(31),32-hexaene-2,5,8,11,14,30-hexone, Bouvardin, 6-(3-hydroxy-N,O-dimethyl-L-tyrosine)-5-(N-methyl-L-tyrosine)-, Ravii, CHEMBL289601, MBQKTLYFUYNAPZ-FEZMQHRXSA-N, DTXSID701006656, HY-P2045, RA-700, AKOS040747341, FS-7842, DA-57355, CS-0107588, Q27280126, 2,5,11-Trihydroxy-24-methoxy-10-[(4-methoxyphenyl)methyl]-4,7,9,13,15,29-hexamethyl-22-oxa-3,6,9,12,15,29-hexaazatetracyclo[14.12.2.2~18,21~.1~23,27~]tritriaconta-2,5,11,18,20,23(31),24,26,32-nonaene-8,14,30-trione, CYCLO(D-ALANYL-L-ALANYL-N,O-DIMETHYL-L-TYROSYL-L-ALANYL-N-METHYL-L-TYROSYL-3-HYDROXY-N,O-DIMETHYL-L-TYROSYL), CYCLIC (5->6)-ETHER
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 176.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC(C)CC(CC2CCCCC2)C(C)CCC(C)CC2CC3CCC(CC3)CC3CCCC(C3)CC(CC2C)C(C)CC1
Np Classifier Class Cyclic peptides
Deep Smiles COcccccc6))C[C@H]C=O)N[C@@H]C)C=O)NC)[C@H]Ccccccc6))OcccC[C@H]NC%14=O))C))C=O)N[C@@H]C=O)N[C@H]C=O)N%26C)))C))))C))))))ccc6OC
Heavy Atom Count 56.0
Classyfire Class Carboxylic acids and derivatives
Scaffold Graph Node Level OC1CNC(O)C2CC3CCCC(C3)OC3CCC(CC3)CC(NC(O)CNC(O)C(CC3CCCCC3)NC(O)CN1)C(O)N2
Classyfire Subclass Amino acids, peptides, and analogues
Isotope Atom Count 0.0
Molecular Complexity 1420.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name (1S,4R,7S,10S,13S,16S)-24-methoxy-10-[(4-methoxyphenyl)methyl]-4,7,9,13,15,29-hexamethyl-22-oxa-3,6,9,12,15,29-hexazatetracyclo[14.12.2.218,21.123,27]tritriaconta-18,20,23,25,27(31),32-hexaene-2,5,8,11,14,30-hexone
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Organic acids and derivatives
Xlogp 3.3
Gsk 4 400 Rule False
Molecular Formula C41H50N6O9
Scaffold Graph Node Bond Level O=C1CNC(=O)C2Cc3cccc(c3)Oc3ccc(cc3)CC(NC(=O)CNC(=O)C(Cc3ccccc3)NC(=O)CN1)C(=O)N2
Prediction Swissadme 0.0
Inchi Key MBQKTLYFUYNAPZ-FEZMQHRXSA-N
Silicos It Class Poorly soluble
Fcsp3 0.4146341463414634
Logs -3.952
Rotatable Bond Count 4.0
Logd 1.875
Synonyms cyclic hexapeptide ra-viis
Esol Class Poorly soluble
Functional Groups CC(=O)NC, CN(C)C(C)=O, CNC(C)=O, cOC, cOc
Compound Name RA VII
Prediction Hob Swissadme 0.0
Exact Mass 770.364
Formal Charge 0.0
Monoisotopic Mass 770.364
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 770.9
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -7.314937942857145
Inchi InChI=1S/C41H50N6O9/c1-23-36(48)43-24(2)39(51)45(4)31(19-26-9-14-29(54-7)15-10-26)38(50)44-25(3)40(52)47(6)33-20-27-11-16-30(17-12-27)56-35-22-28(13-18-34(35)55-8)21-32(37(49)42-23)46(5)41(33)53/h9-18,22-25,31-33H,19-21H2,1-8H3,(H,42,49)(H,43,48)(H,44,50)/t23-,24+,25+,31+,32+,33+/m1/s1
Smiles C[C@@H]1C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H]2CC3=CC=C(C=C3)OC4=C(C=CC(=C4)C[C@@H](C(=O)N1)N(C2=O)C)OC)C)C)CC5=CC=C(C=C5)OC)C)C
Nring 6.0
Np Classifier Biosynthetic Pathway Amino acids and Peptides
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Oligopeptides

  • 1. Outgoing r'ship FOUND_IN to/from Rubia Cordifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all