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(5Alpha,8Alpha)-2-Oxo-1(10),3,7(11)-Guaiatrien-12,8-Olide

PubChem CID: 3013843

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Compound Synonyms CHEMBL501260, (5alpha,8alpha)-2-oxo-1(10),3,7(11)-guaiatrien-12,8-olide, (3aS,8aS)-1,5,8-trimethyl-3a,4,8a,9-tetrahydroazuleno[6,5-b]furan-2,6-dione, (3aS,8aS)-1,5,8-trimethyl-3a,4,8a,9-tetrahydroazuleno(6,5-b)furan-2,6-dione, BDBM50259850, azuleno[6,5-b]furan-2,7-dione, 4,4a,9,9a-tetrahydro-3,5,8-trimethyl-, (4aS,9aS)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 43.4
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCC3C(C)CCC3CC2C1
Np Classifier Class Guaiane sesquiterpenoids
Deep Smiles CC=CC[C@H]C=CC=O)C5=CC[C@@H]%10OC%13=O)))))C)))))C
Heavy Atom Count 18.0
Classyfire Class Dihydrofurans
Scaffold Graph Node Level OC1CC2CC3CCC(O)C3CCC2O1
Classyfire Subclass Furanones
Isotope Atom Count 0.0
Molecular Complexity 560.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 2.0
Uniprot Id P08684, P10635
Iupac Name (3aS,8aS)-1,5,8-trimethyl-3a,4,8a,9-tetrahydroazuleno[6,5-b]furan-2,6-dione
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Target Id NPT109
Xlogp 1.0
Gsk 4 400 Rule True
Molecular Formula C15H16O3
Scaffold Graph Node Bond Level O=C1C=C2CC3C=CC(=O)C3=CCC2O1
Prediction Swissadme 0.0
Inchi Key CTXCWPVELDJQRF-GWCFXTLKSA-N
Silicos It Class Soluble
Fcsp3 0.4666666666666667
Logs -4.373
Rotatable Bond Count 0.0
Logd 3.115
Synonyms (5alpha,8alpha)-2-oxo-1(10),3,7(11)-guaiatrien-12,8-olide
Esol Class Very soluble
Functional Groups CC1=C(C)C(=O)OC1, CC1=CC(=O)C(=C(C)C)C1
Compound Name (5Alpha,8Alpha)-2-Oxo-1(10),3,7(11)-Guaiatrien-12,8-Olide
Prediction Hob Swissadme 0.0
Exact Mass 244.11
Formal Charge 0.0
Monoisotopic Mass 244.11
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 244.28
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -1.9719979999999997
Inchi InChI=1S/C15H16O3/c1-7-4-12(16)14-8(2)5-13-11(6-10(7)14)9(3)15(17)18-13/h4,10,13H,5-6H2,1-3H3/t10-,13-/m0/s1
Smiles CC1=C2[C@@H](CC3=C(C(=O)O[C@H]3C1)C)C(=CC2=O)C
Nring 3.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Sesquiterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Piper Cubeba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all