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4H-Indolo[3,2,1-de][1,5]naphthyridin-4-one, 5-methoxy-

PubChem CID: 3012902

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Compound Synonyms CHEMBL517641, 4H-Indolo[3,2,1-de][1,5]naphthyridin-4-one, 5-methoxy-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 44.1
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2C3CCCCC3C3CCCC1C32
Np Classifier Class Carboline alkaloids
Deep Smiles COccncccccc6cc9cc%13=O))ncc6
Heavy Atom Count 19.0
Classyfire Class Indolonaphthyridine alkaloids
Scaffold Graph Node Level OC1CCN2C3CCCCC3C3CCNC1C32
Isotope Atom Count 0.0
Molecular Complexity 434.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 3-methoxy-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-2,5,7,9(16),10,12,14-heptaen-4-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.5
Gsk 4 400 Rule True
Molecular Formula C15H10N2O2
Scaffold Graph Node Bond Level O=c1ccn2c3ccccc3c3ccnc1c32
Prediction Swissadme 0.0
Inchi Key ARKHSSXCCQCKAF-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.0666666666666666
Logs -4.149
Rotatable Bond Count 1.0
Logd 1.911
Synonyms drymaritin
Esol Class Soluble
Functional Groups c=O, cOC, cn(c)c, cnc
Compound Name 4H-Indolo[3,2,1-de][1,5]naphthyridin-4-one, 5-methoxy-
Prediction Hob Swissadme 0.0
Exact Mass 250.074
Formal Charge 0.0
Monoisotopic Mass 250.074
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 250.25
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.626251294736842
Inchi InChI=1S/C15H10N2O2/c1-19-12-8-17-11-5-3-2-4-9(11)10-6-7-16-13(14(10)17)15(12)18/h2-8H,1H3
Smiles COC1=CN2C3=CC=CC=C3C4=C2C(=NC=C4)C1=O
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

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  • 2. Outgoing r'ship FOUND_IN to/from Aleurites Cordata (Plant) Rel Props:Reference:
  • 3. Outgoing r'ship FOUND_IN to/from Alnus Cordata (Plant) Rel Props:Reference:
  • 4. Outgoing r'ship FOUND_IN to/from Aralia Cordata (Plant) Rel Props:Reference:
  • 5. Outgoing r'ship FOUND_IN to/from Buddleja Cordata (Plant) Rel Props:Reference:
  • 6. Outgoing r'ship FOUND_IN to/from Carpinus Cordata (Plant) Rel Props:Reference:
  • 7. Outgoing r'ship FOUND_IN to/from Circaea Cordata (Plant) Rel Props:Reference:
  • 8. Outgoing r'ship FOUND_IN to/from Drymaria Cordata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Drymaria Diandra (Plant) Rel Props:Reference:
  • 10. Outgoing r'ship FOUND_IN to/from Eucalyptus Cordata (Plant) Rel Props:Reference:
  • 11. Outgoing r'ship FOUND_IN to/from Ficus Cordata (Plant) Rel Props:Reference:
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  • 14. Outgoing r'ship FOUND_IN to/from Mikania Cordata (Plant) Rel Props:Reference:
  • 15. Outgoing r'ship FOUND_IN to/from Orymaria Cordata (Plant) Rel Props:Reference:
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  • 19. Outgoing r'ship FOUND_IN to/from Telosma Cordata (Plant) Rel Props:Reference:
  • 20. Outgoing r'ship FOUND_IN to/from Tilia Cordata (Plant) Rel Props:Reference:
  • 21. Outgoing r'ship FOUND_IN to/from Trichosanthes Cordata (Plant) Rel Props:Reference:
  • 22. Outgoing r'ship FOUND_IN to/from Uncaria Cordata (Plant) Rel Props:Reference: