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Hemanthidine

PubChem CID: 3002914

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Compound Synonyms Pancratine, Hemanthidine, Haemanthidine, 466-73-9, 6DB9318OGJ, UNII-6DB9318OGJ, HEMANTHIDINE, (-)-, (1S,11S,13S,15S,18R)-15-methoxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraene-11,18-diol, 3H,6H-5,11B-ETHANO(1,3)DIOXOLO(4,5-J)PHENANTHRIDINE-6,12-DIOL, 4,4A-DIHYDRO-3-METHOXY-, (3S,4AS,5S,6S,11BS,12R)-, 3H,6H-5,11B-ETHANO(1,3)DIOXOLO(4,5-J)PHENANTHRIDINE-6,12-DIOL, 4,4A-DIHYDRO-3-METHOXY-, (3S-(3.ALPHA.,4A.ALPHA.,5.BETA.,6.ALPHA.,11B.BETA.,12S*))-, 4a.beta.,5.alpha.,11b.alpha.-Crinan-6.beta.,12-diol, 1,2-didehydro-3.beta.-methoxy-, (12R)-, (1S,11S,13S,15S,18R)-15-methoxy-5,7-dioxa-12-azapentacyclo(10.5.2.01,13.02,10.04,8)nonadeca-2,4(8),9,16-tetraene-11,18-diol, (-)-Haemanthidine, CHEMBL465820, 3H,6H-5,11b-Ethano(1,3)dioxolo(4,5-j)phenanthridine, crinan-6,11-diol deriv., 3H,6H-5,11b-Ethano[1,3]dioxolo[4,5-j]phenanthridine, crinan-6,11-diol deriv., Crinan-6,11-diol, 1,2-didehydro-3-methoxy-, (3beta,5alpha,6beta,11R,13beta,19alpha)-, Crinan-6,11-diol, 1,2-didehydro-3-methoxy-, (3.beta.,5.alpha.,6.beta.,11R,13.beta.,19.alpha.)-, Crinan-7,18-diol, 1,2-didehydro-3-methoxy-, (3.beta.,5.beta.,6.alpha.,7.beta.,17.alpha.,18R)-, Q27896532, 4abeta,5alpha,11balpha-Crinan-6beta,12-diol, 1,2-didehydro-3beta-methoxy-, (12R)-, Crinan-7,18-diol, 1,2-didehydro-3-methoxy-, (3beta,5beta,6alpha,7beta,17alpha,18R)-, 3H,6H-5,11B-ETHANO(1,3)DIOXOLO(4,5-J)PHENANTHRIDINE-6,12-DIOL, 4,4A-DIHYDRO-3-METHOXY-, (3S-(3ALPHA,4AALPHA,5BETA,6ALPHA,11BBETA,12S*))-, 3H,6H-5,11b-Ethano[1,3]dioxolo[4,5-j]phenanthridine-6,12-diol, 4,4a-dihydro-3-methoxy-, (3S,4aS,11bS)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 71.4
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CC4CCC5(CCCCC45)C3CC2C1
Np Classifier Class Amarylidaceae alkaloids, Isoquinoline alkaloids
Deep Smiles CO[C@@H]C=C[C@][C@H]C6)NC[C@@H]5O)))[C@H]cc6ccOCOc5c9)))))))))O
Heavy Atom Count 23.0
Classyfire Class Amaryllidaceae alkaloids
Scaffold Graph Node Level C1CCC23CCN(CC4CC5OCOC5CC42)C3C1
Classyfire Subclass Crinine- and haemanthamine-type amaryllidaceae alkaloids
Isotope Atom Count 0.0
Molecular Complexity 527.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name (1S,11S,13S,15S,18R)-15-methoxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraene-11,18-diol
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 0.7
Gsk 4 400 Rule True
Molecular Formula C17H19NO5
Scaffold Graph Node Bond Level C1=CC23CCN(Cc4cc5c(cc42)OCO5)C3CC1
Inchi Key ZSTPNQLNQBRLQF-UAQFGPKRSA-N
Silicos It Class Soluble
Rotatable Bond Count 1.0
Synonyms haemanthidinc, haemanthidine, pancratine
Esol Class Soluble
Functional Groups CC=CC, CO, COC, c1cOCO1, c[C@H](O)N(C)C
Compound Name Hemanthidine
Exact Mass 317.126
Formal Charge 0.0
Monoisotopic Mass 317.126
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 317.34
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C17H19NO5/c1-21-9-2-3-17-11-6-13-12(22-8-23-13)5-10(11)16(20)18(7-15(17)19)14(17)4-9/h2-3,5-6,9,14-16,19-20H,4,7-8H2,1H3/t9-,14+,15+,16+,17+/m1/s1
Smiles CO[C@H]1C[C@H]2[C@@]3(C=C1)[C@H](CN2[C@H](C4=CC5=C(C=C34)OCO5)O)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

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