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1-O-[(2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraen-3-yl] 4-O-methyl (2S)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate

PubChem CID: 29927670

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Compound Synonyms harringtonine, 26833-85-2, AKOS015965555, AC-20253, AC-34766, Q63408611, (9R)-O~3~-[(2S)-2,5-dihydroxy-2-(2-methoxy-2-oxoethyl)-5-methylhexanoyl]cephalotaxine
Topological Polar Surface Area 124.0
Hydrogen Bond Donor Count 2.0
Heavy Atom Count 38.0
Isotope Atom Count 0.0
Molecular Complexity 953.0
Database Name cmaup_ingredients;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name 1-O-[(2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraen-3-yl] 4-O-methyl (2S)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate
Prediction Hob 0.0
Xlogp 0.5
Molecular Formula C28H37NO9
Prediction Swissadme 0.0
Inchi Key HAVJATCHLFRDHY-ZBVBGGFBSA-N
Fcsp3 0.6428571428571429
Logs -5.827
Rotatable Bond Count 10.0
Logd 3.897
Compound Name 1-O-[(2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraen-3-yl] 4-O-methyl (2S)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate
Prediction Hob Swissadme 0.0
Exact Mass 531.247
Formal Charge 0.0
Monoisotopic Mass 531.247
Hydrogen Bond Acceptor Count 10.0
Molecular Weight 531.6
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Esol -2.882574505263161
Inchi InChI=1S/C28H37NO9/c1-26(2,32)8-9-28(33,15-22(30)35-4)25(31)38-24-21(34-3)14-27-7-5-10-29(27)11-6-17-12-19-20(37-16-36-19)13-18(17)23(24)27/h12-14,23-24,32-33H,5-11,15-16H2,1-4H3/t23-,24-,27+,28+/m1/s1
Smiles CC(C)(CC[C@](CC(=O)OC)(C(=O)O[C@H]1[C@H]2C3=CC4=C(C=C3CCN5[C@@]2(CCC5)C=C1OC)OCO4)O)O
Nring 2.0
Defined Bond Stereocenter Count 0.0