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O-Methyltubulosine

PubChem CID: 280145

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Compound Synonyms O-Methyltubulosine, 5263-31-0, (-)-O-Methyltubulosine, Tubulosine, O-methyl-, Tubulosan, 8',10,11-trimethoxy-, NSC-131548, EC2567JY2T, METHYLTUBULOSINE, NSC 131548, UNII-EC2567JY2T, NZ-72, (2S,3R,11bS)-3-ethyl-9,10-dimethoxy-2-[[(1R)-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine, (2S,3R,11BS)-3-ETHYL-1,3,4,6,7,11B-HEXAHYDRO-9,10-DIMETHOXY-2-(((1R)-2,3,4,9-TETRAHYDRO-6-METHOXY-1H-PYRIDO(3,4-B)INDOL-1-YL)METHYL)-2H-BENZO(A)QUINOLIZINE, 2H-BENZO(A)QUINOLIZINE, 3-ETHYL-1,3,4,6,7,11B-HEXAHYDRO-9,10-DIMETHOXY-2-(((1R)-2,3,4,9-TETRAHYDRO-6-METHOXY-1H-PYRIDO(3,4-B)INDOL-1-YL)METHYL)-, (2S,3R,11BS)-, TUBULOSINE, O-METHYL, Tubulosan,10,11-trimethoxy-, NSC131548, Tubulosan, 8',10,11-trimethoxy-(9CI)
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 58.8
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCC1CCC(CC3CCCC4C5CCCCC5CC34)CC12
Np Classifier Class Carboline alkaloids, Isoquinoline alkaloids, Terpenoid tetrahydroisoquinoline alkaloids
Deep Smiles COcccccc6)cCCN[C@@H]c6[nH]9))C[C@H]C[C@@H]NC[C@@H]6CC))))CCcc6ccOC))cc6)OC
Heavy Atom Count 36.0
Classyfire Class Harmala alkaloids
Scaffold Graph Node Level C1CCC2C(C1)CCN1CCC(CC3NCCC4C5CCCCC5NC34)CC21
Isotope Atom Count 0.0
Molecular Complexity 738.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name (2S,3R,11bS)-3-ethyl-9,10-dimethoxy-2-[[(1R)-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 4.9
Gsk 4 400 Rule False
Molecular Formula C30H39N3O3
Scaffold Graph Node Bond Level c1ccc2c(c1)CCN1CCC(CC3NCCc4c3[nH]c3ccccc43)CC21
Inchi Key YQCYWTNBMKOEPG-CWYCPHMGSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 6.0
Synonyms dimethyltubulosine
Esol Class Moderately soluble
Functional Groups CN(C)C, CNC, cOC, c[nH]c
Compound Name O-Methyltubulosine
Exact Mass 489.299
Formal Charge 0.0
Monoisotopic Mass 489.299
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 489.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C30H39N3O3/c1-5-18-17-33-11-9-19-14-28(35-3)29(36-4)16-23(19)27(33)13-20(18)12-26-30-22(8-10-31-26)24-15-21(34-2)6-7-25(24)32-30/h6-7,14-16,18,20,26-27,31-32H,5,8-13,17H2,1-4H3/t18-,20-,26+,27-/m0/s1
Smiles CC[C@H]1CN2CCC3=CC(=C(C=C3[C@@H]2C[C@@H]1C[C@@H]4C5=C(CCN4)C6=C(N5)C=CC(=C6)OC)OC)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids, Tyrosine alkaloids