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Phosphatase

PubChem CID: 2723710

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Compound Synonyms 333338-18-4, 4-Nitrophenyl phosphate disodium salt hexahydrate, Sodium 4-nitrophenyl phosphate hexahydrate, Phosphatase, disodium, (4-nitrophenyl) phosphate, hexahydrate, Phosphatase substrate, MFCD00066288, Phosphoric acid, mono(4-nitrophenyl) ester, sodium salt, hydrate(1:2:6)OTHER CA INDEX NAMES:Phosphoric acid, mono(4-nitrophenyl) ester, disodium salt, hexahydrate, 4-Nitrophenyl phosphate (disodium salt hexahydrate), 9013-05-2, Phosphoesterase, p-nitrophenyl phosphate disodium salt hexahydrate, Phosphoric acid esterase, Alkyl phosphomonoesterase, disodium hexahydrate p-nitrophenyl phosphate, disodium,(4-nitrophenyl) phosphate,hexahydrate, DTXSID60369089, KAKKHKRHCKCAGH-UHFFFAOYSA-L, DTXSID901053934, EINECS 232-744-9, AKOS016015228, Sodium4-nitrophenylphosphatehexahydrate, DA-06779, PD150667, SY074980, D91659, 4-Nitrophenyl phosphate disodium salt hexahydrate (PNPP), Disodium 4-nitrophenyl phosphate hexahydrate [for Biochemical Research], 232-744-9
Topological Polar Surface Area 124.0
Hydrogen Bond Donor Count 6.0
Inchi Key KAKKHKRHCKCAGH-UHFFFAOYSA-L
Rotatable Bond Count 1.0
Heavy Atom Count 22.0
Compound Name Phosphatase
Description Phosphatase, also known as 4-nitrophenylphosphate or dipotassium nitrophenylphosphate, is a member of the class of compounds known as phenyl phosphates. Phenyl phosphates are aromatic organooxygen compounds containing a phosphate group, which is O-esterified with a phenyl group. Phosphatase can be found in a number of food items such as french plantain, fenugreek, pineapple, and horseradish, which makes phosphatase a potential biomarker for the consumption of these food products. A phosphatase is an enzyme that uses water to cleave a phosphoric acid monoester into a phosphate ion and an alcohol. Because a phosphatase enzyme catalyzes the hydrolysis of its substrate, it is a subcategory of hydrolases. Phosphatase enzymes are essential to many biological functions, because phosphorylation (e.g. by protein kinases) and dephosphorylation (by phosphatases) serve diverse roles in cellular regulation and signaling. Whereas phosphatases remove phosphate groups from molecules, kinases catalyze the transfer of phosphate groups to molecules from ATP. Together, kinases and phosphatases direct a form of post-translational modification that is essential to the cell's regulatory network. Phosphatase enzymes are not to be confused with phosphorylase enzymes, which catalyze the transfer of a phosphate group from hydrogen phosphate to an acceptor. Due to their prevalence in cellular regulation, phosphatases are an area of interest for pharmaceutical research .
Exact Mass 371.021
Formal Charge 0.0
Monoisotopic Mass 371.021
Isotope Atom Count 0.0
Molecular Complexity 238.0
Hydrogen Bond Acceptor Count 12.0
Molecular Weight 371.14
Database Name fooddb_chem_all;pubchem
Covalent Unit Count 9.0
Defined Atom Stereocenter Count 0.0
Iupac Name disodium, (4-nitrophenyl) phosphate, hexahydrate
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Inchi InChI=1S/C6H6NO6P.2Na.6H2O/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12, , , , , , , , /h1-4H,(H2,10,11,12), , , 6*1H2/q, 2*+1, , , , , , /p-2
Smiles C1=CC(=CC=C1[N+](=O)[O-])OP(=O)([O-])[O-].O.O.O.O.O.O.[Na+].[Na+]
Defined Bond Stereocenter Count 0.0
Molecular Formula C6H16NNa2O12P

  • 1. Outgoing r'ship FOUND_IN to/from Ananas Comosus (Plant) Rel Props:Source_db:fooddb_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Armoracia Rusticana (Plant) Rel Props:Source_db:fooddb_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Castanea Sativa (Plant) Rel Props:Source_db:fooddb_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Helianthus Tuberosus (Plant) Rel Props:Source_db:fooddb_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Lens Culinaris (Plant) Rel Props:Source_db:fooddb_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Trigonella Foenum-Graecum (Plant) Rel Props:Source_db:fooddb_chem_all