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1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-phenylpropan-1-one

PubChem CID: 270058

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Compound Synonyms 3791-76-2, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenylpropan-1-one, Dihydroflavokawin B, 1-(2-Hydroxy-4,6-dimethoxy-phenyl)-3-phenyl-propan-1-one, CHEMBL492166, dihydroflavokawain b, NSC112157, SCHEMBL1937964, DTXSID10296851, BDBM50491167, LMPK12120513, AKOS026670572, NSC-112157, DB-017130, AM-573/21093005, Dihydroflavokawin B (2'-Hydroxy-4',6'-dimethoxydihydrochalcone)
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 55.8
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CCC1CCCCC1)C1CCCCC1
Np Classifier Class Chalcones
Deep Smiles COcccO)ccc6)OC)))C=O)CCcccccc6
Heavy Atom Count 21.0
Classyfire Class Linear 1,3-diarylpropanoids
Scaffold Graph Node Level OC(CCC1CCCCC1)C1CCCCC1
Classyfire Subclass Chalcones and dihydrochalcones
Isotope Atom Count 0.0
Molecular Complexity 325.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id n.a., P14916
Iupac Name 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenylpropan-1-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 3.6
Gsk 4 400 Rule True
Molecular Formula C17H18O4
Scaffold Graph Node Bond Level O=C(CCc1ccccc1)c1ccccc1
Prediction Swissadme 0.0
Inchi Key JAJFQMZJIQDRSX-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.2352941176470588
Logs -4.583
Rotatable Bond Count 6.0
Logd 3.443
Synonyms lapathone
Esol Class Soluble
Functional Groups cC(C)=O, cO, cOC
Compound Name 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-phenylpropan-1-one
Prediction Hob Swissadme 0.0
Exact Mass 286.121
Formal Charge 0.0
Monoisotopic Mass 286.121
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 286.32
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.928984542857143
Inchi InChI=1S/C17H18O4/c1-20-13-10-15(19)17(16(11-13)21-2)14(18)9-8-12-6-4-3-5-7-12/h3-7,10-11,19H,8-9H2,1-2H3
Smiles COC1=CC(=C(C(=C1)OC)C(=O)CCC2=CC=CC=C2)O
Nring 2.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Flavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Anabasis Brevifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Pentanema Indicum (Plant) Rel Props:Source_db:npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Persicaria Lapathifolia (Plant) Rel Props:Reference:ISBN:9788185042145