This website is for informational and educational purposes only. Please do not self-medicate; contact a medical professional for advice before administration. This website is for informational and educational purposes only. Please do not self-medicate; contact a medical professional for advice before administration.

Dihydrocucurbitacin B

PubChem CID: 267250

Connections displayed (default: 10).
Loading graph...

Compound Synonyms DIHYDROCUCURBITACIN B, 13201-14-4, 23,24-dihydrocucurbitacin B, CHEBI:62217, Cucurbitacin B, dihydro-, NSC-106401, (10alpha)-25-(Acetyloxy)-2beta,16alpha,20-trihydroxy-9beta-methyl-19-norlanost-5-ene-3,11,22-trione, (2S,4R)-2,16beta,20-trihydroxy-9beta,10,14-trimethyl-1,11,22-trioxo-4,9-cyclo-9,10-secocholest-5-en-25-yl acetate, [(6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxoheptan-2-yl] acetate, 25-acetoxy-2beta,16alpha,20-trihydroxy-10alpha-cucurbit-5-ene-3,11,22-trione, (2.BETA.,9.BETA.,10.ALPHA.,16.ALPHA.)-25-(ACETYLOXY)-2,16,20-TRIHYDROXY-9-METHYL-19-NORLANOST-5-ENE-3,11,22-TRIONE, 19-NORLANOST-5-ENE-3,11,22-TRIONE, 25-(ACETYLOXY)-2,16,20-TRIHYDROXY-9-METHYL-, (2.BETA.,9.BETA.,10.ALPHA.,16.ALPHA.)-, 2beta,16alpha,20,25-tetrahydroxy-9-methyl-19-nor-9beta,10alpha-lanost-5-ene-3,11,22-trione, 25-acetate, 2beta,16alpha,20,25-tetrahydroxy-9-methyl-3,11,22-trioxo-19-nor-9beta,10alpha-lanost-5-en-25-yl acetate, Cucurbitacin B, 23,24-dihydro-, CHEMBL553851, DTXSID701314710, HY-N4171, NAA20114, NSC106401, AKOS037514506, DA-62878, MS-30184, CS-0032304, NS00094065, C20787, G14140, Q27131690, 25-Acetoxy-2b,16a,20-trihydroxy-10a-cucurbit-5-ene-3,11,22-trione, 25-Acetoxy-2I2,16I+-,20-trihydroxy-10I+--cucurbit-5-ene-3,11,22-trione, (2BETA,9BETA,10ALPHA,16ALPHA)-25-(ACETYLOXY)-2,16,20-TRIHYDROXY-9-METHYL-19-NORLANOST-5-ENE-3,11,22-TRIONE, 19-NORLANOST-5-ENE-3,11,22-TRIONE, 25-(ACETYLOXY)-2,16,20-TRIHYDROXY-9-METHYL-, (2BETA,9BETA,10ALPHA,16ALPHA)-, 2b,16a,20,25-Tetrahydroxy-9-methyl-19-nor-9b,10a-lanost-5-ene-3,11,22-trione, 25-acetate, 2b,16a,20,25-Tetrahydroxy-9-methyl-19-nor-9b,10a-lanost-5-ene-3,11,22-trione, 25-acetic acid, 2b,16a,20,25-Tetrahydroxy-9-methyl-3,11,22-trioxo-19-nor-9b,10a-lanost-5-en-25-yl acetate, 2b,16a,20,25-Tetrahydroxy-9-methyl-3,11,22-trioxo-19-nor-9b,10a-lanost-5-en-25-yl acetic acid, 2beta,16alpha,20,25-Tetrahydroxy-9-methyl-19-nor-9beta,10alpha-lanost-5-ene-3,11,22-trione, 25-acetic acid, 2beta,16alpha,20,25-Tetrahydroxy-9-methyl-3,11,22-trioxo-19-nor-9beta,10alpha-lanost-5-en-25-yl acetic acid
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 138.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2C(CCC3C4CCCC4CC(C)C23)C1
Np Classifier Class Cucurbitane triterpenoids
Deep Smiles CC=O)OCCCC=O)[C@@][C@H][C@H]O)C[C@@][C@]5C)CC=O)[C@@][C@H]6CC=C[C@H]6C[C@H]O)C=O)C6C)C))))))))))C)))))C)))))O)C)))))C)C
Heavy Atom Count 40.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level OC1CCC2C(CCC3C4CCCC4CC(O)C23)C1
Classyfire Subclass Cucurbitacins
Isotope Atom Count 0.0
Molecular Complexity 1170.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 9.0
Iupac Name [(6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxoheptan-2-yl] acetate
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 2.7
Gsk 4 400 Rule False
Molecular Formula C32H48O8
Scaffold Graph Node Bond Level O=C1CCC2C(=CCC3C4CCCC4CC(=O)C23)C1
Prediction Swissadme 0.0
Inchi Key QZJJDOYZVRUEDY-NRNCYQGDSA-N
Silicos It Class Moderately soluble
Fcsp3 0.8125
Logs -4.453
Rotatable Bond Count 7.0
Logd 2.191
Synonyms 23,24-dihydrocucurbitacin b, dihydrocucurbitacin b
Esol Class Moderately soluble
Functional Groups CC(C)=O, CC=C(C)C, CO, COC(C)=O
Compound Name Dihydrocucurbitacin B
Prediction Hob Swissadme 0.0
Exact Mass 560.335
Formal Charge 0.0
Monoisotopic Mass 560.335
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 560.7
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.555513600000002
Inchi InChI=1S/C32H48O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,19-22,25,34-35,39H,11-16H2,1-9H3/t19-,20+,21-,22+,25+,29+,30-,31+,32+/m1/s1
Smiles CC(=O)OC(C)(C)CCC(=O)[C@@](C)([C@H]1[C@@H](C[C@@]2([C@@]1(CC(=O)[C@@]3([C@H]2CC=C4[C@H]3C[C@@H](C(=O)C4(C)C)O)C)C)C)O)O
Nring 4.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Triterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Citrullus Colocynthis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Cucumis Melo (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Hemsleya Macrosperma (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Trichosanthes Cucumerina (Plant) Rel Props:Reference:ISBN:9788172363093
  • 5. Outgoing r'ship FOUND_IN to/from Trichosanthes Cucumeroides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Trichosanthes Tricuspidata (Plant) Rel Props:Reference:ISBN:9788172363093