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Lignan

PubChem CID: 261166

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Compound Synonyms Lignan, 6549-68-4, ethyl 6,7-dimethoxy-3-methyl-4-oxo-1-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydronaphthalene-2-carboxylate, NSC93090, DTXSID90293944, ethyl 6,7-dimethoxy-3-methyl-4-oxo-1-(3,4,5-trimethoxyphenyl)-2,3-dihydro-1H-naphthalene-2-carboxylate, SCHEMBL30935, CHEBI:25036, DTXCID90245084, NSC-93090, DB-230442, Ethyl 6,7-dimethoxy-3-methyl-4-oxo-1-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydro-2-naphthalenecarboxylate
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 89.5
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC(C2CCCCC2)C2CCCCC12
Np Classifier Class Arylnaphthalene and aryltetralin lignans
Deep Smiles CCOC=O)CCC)C=O)ccC6cccOC))ccc6)OC)))OC)))))))cccc6)OC)))OC
Heavy Atom Count 33.0
Classyfire Class Aryltetralin lignans
Scaffold Graph Node Level OC1CCC(C2CCCCC2)C2CCCCC12
Isotope Atom Count 0.0
Molecular Complexity 655.0
Database Name cmaup_ingredients;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id O81355, Q94KL7, Q94KL8, Q9FUW6
Iupac Name ethyl 6,7-dimethoxy-3-methyl-4-oxo-1-(3,4,5-trimethoxyphenyl)-2,3-dihydro-1H-naphthalene-2-carboxylate
Prediction Hob 0.0
Class Aryltetralin lignans
Veber Rule True
Classyfire Superclass Lignans, neolignans and related compounds
Xlogp 3.8
Superclass Lignans, neolignans and related compounds
Gsk 4 400 Rule False
Molecular Formula C25H30O8
Scaffold Graph Node Bond Level O=C1CCC(c2ccccc2)c2ccccc21
Prediction Swissadme 0.0
Inchi Key PEIBIXYUYBVLDS-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.44
Logs -4.601
Rotatable Bond Count 9.0
Logd 3.002
Synonyms Lignans, Neolignan, Neolignans, lignan
Esol Class Moderately soluble
Functional Groups COC(C)=O, cC(C)=O, cOC
Compound Name Lignan
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 458.194
Formal Charge 0.0
Monoisotopic Mass 458.194
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 458.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic homopolycyclic compounds
Lipinski Rule Of 5 True
Esol -4.73293430909091
Inchi InChI=1S/C25H30O8/c1-8-33-25(27)21-13(2)23(26)16-12-18(29-4)17(28-3)11-15(16)22(21)14-9-19(30-5)24(32-7)20(10-14)31-6/h9-13,21-22H,8H2,1-7H3
Smiles CCOC(=O)C1C(C(=O)C2=CC(=C(C=C2C1C3=CC(=C(C(=C3)OC)OC)OC)OC)OC)C
Nring 3.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Aryltetralin lignans
Np Classifier Superclass Lignans

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