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Strophanthidol

PubChem CID: 258412

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Compound Synonyms Strophanthidol, 560-54-3, k-Strophanthidol, K1K9Y2IT7W, EINECS 209-211-4, NSC 87314, NSC-87314, 3-[(3S,5S,8R,9S,10R,13R,14S,17R)-3,5,14-trihydroxy-10-(hydroxymethyl)-13-methyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, UNII-K1K9Y2IT7W, NSC87314, (3beta,5beta)-3,5,14,19-Tetrahydroxycard-20(22)-enolide, 5beta-Card-20(22)-enolide, 3beta,5,14,19-tetrahydroxy-, 5.beta.-Card-20(22)-enolide, 3.beta.,5,14,19-tetrahydroxy-, 5-beta-CARD-20(22)-ENOLIDE, 3-beta,5,14,19-TETRAHYDROXY-, Card-20(22)-enolide, 3,5,14,19-tetrahydroxy-, (3-beta,5-beta)-, (3.BETA.,5.BETA.)-3,5,14,19-TETRAHYDROXYCARD-20(22)-ENOLIDE, Card-20(22)-enolide, 3,5,14,19-tetrahydroxy-, (3.beta.,5.beta.)-, 3-((3S,5S,8R,9S,10R,13R,14S,17R)-3,5,14-trihydroxy-10-(hydroxymethyl)-13-methyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-17-yl)-2H-furan-5-one, CHEMBL1628279, SCHEMBL21578405, DTXSID401317315, MFCD00056528, AKOS030503911, NCI60_041931, NS00042339, 5.beta.-Card-20(22)-enolide,5,14,19-tetrahydroxy-, WLN: L E5 B666TJ AVH E1 IQ MQ OQ F- CT5O CUTJ EQ, 5beta-Card-20(22)-enolide, 3beta,5,14,19-tetrahydroxy-(8CI), Card-20(22)-enolide, 3,5,14,19-tetrahydroxy-, (3beta,5beta)-, Card-20(22)-enolide,5,14,19-tetrahydroxy-, (3.beta.,5.beta.)-, Card-20(22)-enolide, 3,5,14,19-tetrahydroxy-, (3-beta,5-beta)-(9CI)
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 107.0
Hydrogen Bond Donor Count 4.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC(C2CCC3C2CCC2C4CCCCC4CCC23)C1
Np Classifier Class Cardenolides
Deep Smiles OC[C@]CC[C@@H]C[C@@]6O)CC[C@@H][C@@H]%10CC[C@][C@]6O)CC[C@@H]5C=CC=O)OC5)))))))))C))))))))))O
Heavy Atom Count 29.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level OC1CC(C2CCC3C2CCC2C4CCCCC4CCC23)CO1
Classyfire Subclass Steroid lactones
Isotope Atom Count 0.0
Molecular Complexity 750.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 8.0
Uniprot Id n.a.
Iupac Name 3-[(3S,5S,8R,9S,10R,13R,14S,17R)-3,5,14-trihydroxy-10-(hydroxymethyl)-13-methyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 0.5
Gsk 4 400 Rule False
Molecular Formula C23H34O6
Scaffold Graph Node Bond Level O=C1C=C(C2CCC3C2CCC2C4CCCCC4CCC23)CO1
Prediction Swissadme 1.0
Inchi Key ZNDMLUUNNNHNKC-HZXDTFASSA-N
Silicos It Class Soluble
Fcsp3 0.8695652173913043
Logs -2.978
Rotatable Bond Count 2.0
Logd 1.002
Synonyms strophanthidol
Esol Class Soluble
Functional Groups CC1=CC(=O)OC1, CO
Compound Name Strophanthidol
Prediction Hob Swissadme 1.0
Exact Mass 406.236
Formal Charge 0.0
Monoisotopic Mass 406.236
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 406.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.5245178000000013
Inchi InChI=1S/C23H34O6/c1-20-6-3-17-18(4-8-22(27)11-15(25)2-7-21(17,22)13-24)23(20,28)9-5-16(20)14-10-19(26)29-12-14/h10,15-18,24-25,27-28H,2-9,11-13H2,1H3/t15-,16+,17-,18+,20+,21-,22-,23-/m0/s1
Smiles C[C@]12CC[C@H]3[C@H]([C@]1(CC[C@@H]2C4=CC(=O)OC4)O)CC[C@]5([C@@]3(CC[C@@H](C5)O)CO)O
Nring 5.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Steroids

  • 1. Outgoing r'ship FOUND_IN to/from Antiaris Toxicaria (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Corchorus Olitorius (Plant) Rel Props:Reference:ISBN:9788172363178
  • 3. Outgoing r'ship FOUND_IN to/from Strophanthus Kombe (Plant) Rel Props:Reference:ISBN:9788185042084