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Raunescine

PubChem CID: 251566

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Compound Synonyms RAUNESCINE, Raunescine [MI], 3,4,5-Trimethoxybenzoyl methyl raunescate, NSC-72122, UNII-0063SJ21TG, 117-73-7, 0063SJ21TG, 3beta,20alpha-Yohimban-16beta-carboxylic acid, 17alpha,18beta-dihydroxy-, methyl ester, 18-(3,4,5-trimethoxybenzoate), Yohimban-16-carboxylic acid, 17-hydroxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-, 3.beta.,20.alpha.-Yohimban-16.beta.-carboxylic acid, 17.alpha.,18.beta.-dihydroxy-, methyl ester, 18-(3,4,5-trimethoxybenzoate), YOHIMBAN-16-CARBOXYLIC ACID, 17-HYDROXY-18-((3,4,5-TRIMETHOXYBENZOYL)OXY)-, METHYL ESTER, (3.BETA.,16.BETA.,17.ALPHA.,18.BETA.,20.ALPHA.)-, Raunescin, SCHEMBL7573540, DTXSID00922238, NSC72122, 3,5-Trimethoxybenzoyl methyl raunescate, Q27231324, 3.beta., 17.alpha.,18.beta.-dihydroxy-, methyl ester, 18-(3,4,5-trimethoxybenzoate), Methyl 17-hydroxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate, methyl (1R,15S,17R,18R,19S,20S)-18-hydroxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 120.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CC1CCC2CC3C(CCC4C5CCCCC5CC34)CC2C1)C1CCCCC1
Np Classifier Class Yohimbine-like alkaloids
Deep Smiles COC=O)[C@@H][C@@H]O)[C@@H]C[C@H][C@@H]6C[C@H]NC6)CCcc6[nH]cc5cccc6)))))))))))))))))OC=O)cccOC))ccc6)OC)))OC
Heavy Atom Count 41.0
Classyfire Class Yohimbine alkaloids
Scaffold Graph Node Level OC(OC1CCC2CC3C4NC5CCCCC5C4CCN3CC2C1)C1CCCCC1
Isotope Atom Count 0.0
Molecular Complexity 937.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name methyl (1R,15S,17R,18R,19S,20S)-18-hydroxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 4.1
Gsk 4 400 Rule False
Molecular Formula C31H36N2O8
Scaffold Graph Node Bond Level O=C(OC1CCC2CC3c4[nH]c5ccccc5c4CCN3CC2C1)c1ccccc1
Prediction Swissadme 0.0
Inchi Key UGMYHMZSPHJQHL-UTYXIPFNSA-N
Silicos It Class Poorly soluble
Fcsp3 0.4838709677419355
Logs -4.999
Rotatable Bond Count 8.0
Logd 3.396
Synonyms raunescine
Esol Class Moderately soluble
Functional Groups CN(C)C, CO, COC(C)=O, cC(=O)OC, cOC, c[nH]c
Compound Name Raunescine
Prediction Hob Swissadme 0.0
Exact Mass 564.247
Formal Charge 0.0
Monoisotopic Mass 564.247
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 564.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.672768707317075
Inchi InChI=1S/C31H36N2O8/c1-37-24-11-16(12-25(38-2)29(24)39-3)30(35)41-23-13-17-15-33-10-9-19-18-7-5-6-8-21(18)32-27(19)22(33)14-20(17)26(28(23)34)31(36)40-4/h5-8,11-12,17,20,22-23,26,28,32,34H,9-10,13-15H2,1-4H3/t17-,20+,22-,23-,26+,28+/m1/s1
Smiles COC1=CC(=CC(=C1OC)OC)C(=O)O[C@@H]2C[C@@H]3CN4CCC5=C([C@H]4C[C@@H]3[C@@H]([C@H]2O)C(=O)OC)NC6=CC=CC=C56
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Aegiceras Corniculatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Rauvolfia Serpentina (Plant) Rel Props:Reference:https://doi.org/10.1186/s12906-015-0683-7
  • 3. Outgoing r'ship FOUND_IN to/from Rauvolfia Tetraphylla (Plant) Rel Props:Reference:ISBN:9780387706375; ISBN:9788172361150
  • 4. Outgoing r'ship FOUND_IN to/from Rauvolfia Verticillata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all