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Vincristine Sulfate

PubChem CID: 249332

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Compound Synonyms Vincristine sulfate, 2068-78-2, Kyocristine, Vincristine sulphate, Vincrisul, Oncovin, Novopharm, Leurocristine sulfate, NSC 67574, Onkovin, Vincrex, Marqibo, Vincristine, sulfate, 22-oxovincaleukoblastine sulfate, Leurocristine, sulfate, VCR sulfate, NSC67574, rel-Vincristine Sulfate, Vincaleukoblastine, 22-oxo-, sulfate (1:1), Leurocristine sulfate (1:1), Vincristine Sulfate PFS, Marqibo Kit, DTXSID8044331, Lilly 37231, CHEBI:79401, LILLY-37231, Leurocristine sulfate (1:1) (salt), NSC-67574, Leurocristine, sulfate (1:1) (salt), 1217704-93-2, MLS002702994, Vincosid, VINCRISTINE SULFATE (IARC), VINCRISTINE SULFATE (MART.), VINCRISTINE SULFATE (USP-RS), Vincristini sulfas, Oncovin (Lilly), Vincasar (TN), VINCRISTINE SULFATE (EP MONOGRAPH), Marqibo (TN), Oncovin (TN), Vincrex (TN), VINCRISTINE SULFATE (USP MONOGRAPH), MFCD08706469, Sulfate, Vincristine, LCR SULPHATE, VCR SULPHATE, Vincristine sulphate Salt, Vincristine sulfate liposome, SCHEMBL3710, LEUROCRISTINE SULPHATE, CHEMBL501867, DTXCID6024331, HY-N0488R, Leurocristine (sulfate), NSC-67574 (sulfate), 22-Oxovincaleukoblastine (sulfate), Vincristine (sulfate) (Standard), HMS3414L13, HMS3678L11, AKOS015895862, FV28696, NS00076429, V0129, LCR, VCR, D02197, DES-NA-METHYL-NA-FORMYLVINBLASTINE SULPHATE, 22-OXOVINCALEUKOBLASTINE SULFATE (1:1) (SALT), 218-190-0, 22-Oxovincaleukoblastine sulfate salt, (2alpha,2'beta,3alpha,4alpha,5beta,19beta)-22-Oxovincaleukoblastine sulfate (1:1), methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate, sulfuric acid, methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-9-((3S,5S,7S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-6-formyl-5-hydroxy-8-methoxy-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate sulfate, Methyl (3aR,4R,5S,5aR,10bR,13aR)-4-acetoxy-3a-ethyl-9-((5S,7R,9S)-5-ethyl-5-hydroxy-9-methoxycarbonyl-1,4,5,6,7,8,9,10-octahydro-3,7-methano-3-azacycloundecino(5,4-b)indol-9-yl)-6-formyl-5-hydroxy-8-methoxy-3a,4,5,5a,6,11,12,13a-octahydro-1H-indolizino(8,1-cd)carbazole-5-carboxylate monosulfate
Topological Polar Surface Area 254.0
Hydrogen Bond Donor Count 5.0
Inchi Key AQTQHPDCURKLKT-JKDPCDLQSA-N
Rotatable Bond Count 10.0
Heavy Atom Count 65.0
Compound Name Vincristine Sulfate
Exact Mass 922.367
Formal Charge 0.0
Monoisotopic Mass 922.367
Isotope Atom Count 0.0
Molecular Complexity 1830.0
Hydrogen Bond Acceptor Count 16.0
Molecular Weight 923.0
Database Name npass_chem_all;pubchem
Covalent Unit Count 2.0
Uniprot Id n.a., O42275, P81908, O95342, Q92887, O15438, O15439
Defined Atom Stereocenter Count 9.0
Iupac Name methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate, sulfuric acid
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Inchi InChI=1S/C46H56N4O10.H2O4S/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6, 1-5(2,3)4/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3, (H2,1,2,3,4)/t28-,37+,38-,39-,42+,43-,44-,45+,46+, /m1./s1
Smiles CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
Defined Bond Stereocenter Count 0.0
Molecular Formula C46H58N4O14S