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Methyl 20-methyl-8,16-diazahexacyclo[10.6.1.112,18.01,9.02,7.016,19]icosa-2,4,6,13-tetraene-10-carboxylate

PubChem CID: 24190768

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Compound Synonyms Vindolinine, hydrochloride, NSC114348, CHEMBL1980833, NSC-114348
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 41.6
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CCC34CCCC5CC(C3)C12C54
Np Classifier Class Aspidosperma type
Deep Smiles COC=O)CCCC=CCNC6CC%10Ncc5cccc6))))))))CC9C))C5.Cl
Heavy Atom Count 26.0
Classyfire Class Indoles and derivatives
Scaffold Graph Node Level C1CCC2C(C1)NC1CCC34CCCN5CC(C3)C12C54
Classyfire Subclass Carbazoles
Isotope Atom Count 0.0
Molecular Complexity 662.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name methyl 20-methyl-8,16-diazahexacyclo[10.6.1.112,18.01,9.02,7.016,19]icosa-2,4,6,13-tetraene-10-carboxylate, hydrochloride
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Gsk 4 400 Rule True
Molecular Formula C21H25ClN2O2
Scaffold Graph Node Bond Level C1=CC23CCC4Nc5ccccc5C45C(CN(C1)C25)C3
Inchi Key NLXUZHWMDFTHOU-UHFFFAOYSA-N
Silicos It Class Soluble
Rotatable Bond Count 2.0
Synonyms vindolinine hydrochloride
Esol Class Moderately soluble
Functional Groups CC=CC, CN(C)C, COC(C)=O, Cl, cNC
Compound Name Methyl 20-methyl-8,16-diazahexacyclo[10.6.1.112,18.01,9.02,7.016,19]icosa-2,4,6,13-tetraene-10-carboxylate, hydrochloride
Exact Mass 372.16
Formal Charge 0.0
Monoisotopic Mass 372.16
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 372.9
Gi Absorption True
Covalent Unit Count 2.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H24N2O2.ClH/c1-12-15-11-23-9-5-8-20(12)10-13(18(24)25-2)17-21(15,19(20)23)14-6-3-4-7-16(14)22-17, /h3-8,12-13,15,17,19,22H,9-11H2,1-2H3, 1H
Smiles CC1C2CN3CC=CC14C3C25C(C(C4)C(=O)OC)NC6=CC=CC=C56.Cl
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Reference:ISBN:9788185042053