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N-deacetyl-N-formylcolchicine

PubChem CID: 23890

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Compound Synonyms Gloriosine, 7411-12-3, N-Formyldeacetylcolchicine, N-Deacetyl-N-formylcolchicine, N-Deacetyl-N-formyl Colchicine, NSC 403142, N-Formyldesacetylcolchicine, Formyldescaetylcolchicine, N-, N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]formamide, COLCHICINE, N-DEACETYL-N-FORMYL-, U02803H7OJ, NSC-403142, BRN 2824080, DTXSID80225057, NSC403142, Formamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-, 4-14-00-00942 (Beilstein Handbook Reference), FORMAMIDE, N-((7S)-5,6,7,9-TETRAHYDRO-1,2,3,10-TETRAMETHOXY-9-OXOBENZO(A)HEPTALEN-7-YL)-, N-((7S)-5,6,7,9-TETRAHYDRO-1,2,3,10-TETRAMETHOXY-9-OXOBENZO(A)HEPTALEN-7-YL)FORMAMIDE, N-Formyl-N-deacetylcolchicine, N-Formyl-Deacetylcolchicine, CHEMBL85710, UNII-U02803H7OJ, GTPL7526, SCHEMBL4069971, DTXCID80147548, CHEBI:138826, FORMYLDESACETYLCOLCHICINE, N-, MFCD00468038, AKOS017343603, CCG-208385, NCGC00163534-01, NCGC00163534-02, PD047744, COLCHICINE IMPURITY A [EP IMPURITY], Gloriosine (N-Deacetyl-N-formyl-colchicin), NS00094808, C19981, G87062, SR-05000002280, Q9268800, SR-05000002280-2, Formamide,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-, Formamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-, N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]formamide, 630-568-0, Formamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-(9CI)
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 83.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCCC2C(CCCC3CCCCC32)C1
Np Classifier Class Phenethylisoquinoline alkaloids
Deep Smiles O=CN[C@H]CCcc-cc7cc=O)ccc7))OC)))))))cOC))ccc6)OC)))OC
Heavy Atom Count 28.0
Classyfire Class Tropones
Scaffold Graph Node Level OC1CCCC2C(CCCC3CCCCC32)C1
Isotope Atom Count 0.0
Molecular Complexity 697.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 1.0
Uniprot Id Q92830, O42275, P81908
Iupac Name N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]formamide
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Hydrocarbon derivatives
Xlogp 1.0
Gsk 4 400 Rule True
Molecular Formula C21H23NO6
Scaffold Graph Node Bond Level O=c1cccc2c(c1)CCCc1ccccc1-2
Prediction Swissadme 0.0
Inchi Key HDSXDWASQCHADG-HNNXBMFYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.3333333333333333
Logs -2.996
Rotatable Bond Count 5.0
Logd 1.594
Synonyms gloriosine, n-formyl-desacetylcolchicine, n-formyl-n-deacetylcolchicine, n-formyldeacetyl colchicine, n-formyldeacetylcolchicine
Esol Class Soluble
Functional Groups CNC=O, c=O, cOC
Compound Name N-deacetyl-N-formylcolchicine
Prediction Hob Swissadme 0.0
Exact Mass 385.153
Formal Charge 0.0
Monoisotopic Mass 385.153
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 385.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -1.19105062857143
Inchi InChI=1S/C21H23NO6/c1-25-17-8-6-13-14(10-16(17)24)15(22-11-23)7-5-12-9-18(26-2)20(27-3)21(28-4)19(12)13/h6,8-11,15H,5,7H2,1-4H3,(H,22,23)/t15-/m0/s1
Smiles COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC=O
Nring 3.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Colchicum Luteum (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788172362140; ISBN:9788185042084
  • 2. Outgoing r'ship FOUND_IN to/from Dalbergia Melanoxylon (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Delphinium Consolida (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Gloriosa Superba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Iphigenia Indica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Pinus Palustris (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Pinus Roxburghii (Plant) Rel Props:Source_db:npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Thermopsis Lanceolata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all