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Colchicine, N-methyl-

PubChem CID: 23758

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Compound Synonyms N-Methylcolchicine, COLCHICINE, N-METHYL-, 7336-40-5, N-Acetylcolchamine, N-Acetyldemecolcine, N-methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide, N-Acetylcolcemid, NSC 403155, BRN 2825013, Acetamide, N-methyl-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-, NSC403155, Acetamide, N-methyl-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, CHEMBL89261, DTXSID50223606, FS-7403, NSC-403155, DA-76223, N-methyl-N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.0(2),?]hexadeca-1(16),2,4,6,11,14-hexaen-10-yl]acetamide
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 74.3
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCCC2C(CCCC3CCCCC32)C1
Np Classifier Class Phenethylisoquinoline alkaloids
Deep Smiles COccOC))ccc-ccccc=O)cc7[C@H]CC%12))NC=O)C))C))))))OC))))))c6OC
Heavy Atom Count 30.0
Classyfire Class Tropones
Scaffold Graph Node Level OC1CCCC2C(CCCC3CCCCC32)C1
Isotope Atom Count 0.0
Molecular Complexity 770.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name N-methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Veber Rule True
Classyfire Superclass Hydrocarbon derivatives
Xlogp 1.3
Gsk 4 400 Rule False
Molecular Formula C23H27NO6
Scaffold Graph Node Bond Level O=c1cccc2c(c1)CCCc1ccccc1-2
Inchi Key AHZFWPXTSZCLDJ-KRWDZBQOSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 5.0
Synonyms 3-methyl-colchicine
Esol Class Soluble
Functional Groups CC(=O)N(C)C, c=O, cOC
Compound Name Colchicine, N-methyl-
Exact Mass 413.184
Formal Charge 0.0
Monoisotopic Mass 413.184
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 413.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C23H27NO6/c1-13(25)24(2)17-9-7-14-11-20(28-4)22(29-5)23(30-6)21(14)15-8-10-19(27-3)18(26)12-16(15)17/h8,10-12,17H,7,9H2,1-6H3/t17-/m0/s1
Smiles CC(=O)N(C)[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Colchicum Autumnale (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279