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Medicarpin 3-O-glucoside

PubChem CID: 23724664

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Compound Synonyms (-)-Medicocarpin, Medicarpin 3-O-glucoside, 52766-70-8, Medicarpin glucoside, (-)-medicarpin-3-O-glucoside, (2S,3R,4S,5S,6R)-2-[[(6aR,11aR)-9-methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol, CHEBI:80390, beta-D-Glucopyranoside, (6aR,11aR)-6a,11a-dihydro-9-methoxy-6H-benzofuro[3,2-c][1]benzopyran-3-yl, Medicocarpin, Medicarpin-3-O-glucoside, Medicocarpin, (-)-, Medicarpin beta-D-glucoside, CHEMBL517330, 87822F2QJH, DTXSID501312756, HY-N9128, AKOS040762031, Medicarpin 3-O-beta-D-glucopyranoside, CS-0158810, Q27149413, (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{[(1R,10R)-14-methoxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-2,4,6,11(16),12,14-hexaen-5-yl]oxy}oxane-3,4,5-triol, (6aR,11aR)-6a,11a-Dihydro-9-methoxy-6H-benzofuro[3,2-c][1]benzopyran-3-yl beta-D-glucopyranoside, beta-D-Glucopyranoside, 6a,11a-dihydro-9-methoxy-6H-benzofuro[3,2-c][1]benzopyran-3-yl, (6aR-cis)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 127.0
Hydrogen Bond Donor Count 4.0
Pfizer 3 75 Rule True
Scaffold Graph Level C1CCC(CC2CCC3C(CCC4C5CCCCC5CC34)C2)CC1
Np Classifier Class Pterocarpan
Deep Smiles OC[C@H]O[C@@H]Occcccc6)OC[C@@H][C@H]6Occ5cccc6)OC))))))))))))))))))[C@@H][C@H][C@@H]6O))O))O
Heavy Atom Count 31.0
Classyfire Class Isoflavonoids
Description (-)-medicarpin-3-o-glucoside is a member of the class of compounds known as pterocarpans. Pterocarpans are benzo-pyrano-furano-benzene compounds, containing the 6H-[1]benzofuro[3,2-c]chromene skeleton. They are derivatives of isoflavonoids (-)-medicarpin-3-o-glucoside is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). (-)-medicarpin-3-o-glucoside can be found in a number of food items such as pine nut, cupuaçu, olive, and almond, which makes (-)-medicarpin-3-o-glucoside a potential biomarker for the consumption of these food products.
Scaffold Graph Node Level C1CCC(OC2CCC3C(C2)OCC2C4CCCCC4OC32)OC1
Classyfire Subclass Furanoisoflavonoids
Isotope Atom Count 0.0
Molecular Complexity 620.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 7.0
Iupac Name (2S,3R,4S,5S,6R)-2-[[(6aR,11aR)-9-methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
Prediction Hob 1.0
Class Isoflavonoids
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 0.8
Superclass Phenylpropanoids and polyketides
Subclass Furanoisoflavonoids
Gsk 4 400 Rule False
Molecular Formula C22H24O9
Scaffold Graph Node Bond Level c1ccc2c(c1)OC1c3ccc(OC4CCCCO4)cc3OCC21
Prediction Swissadme 1.0
Inchi Key PVEMGMOWXQUWRD-NJAOXFEXSA-N
Silicos It Class Soluble
Fcsp3 0.4545454545454545
Logs -4.168
Rotatable Bond Count 4.0
Logd 1.712
Synonyms Medicarpin 3-O-glucoside, medicarpin 3-o-(6-malonylglucoside)-3-hydroxy-9-methoxypterocarpan, medicocarpin
Esol Class Soluble
Functional Groups CO, cOC, cO[C@@H](C)OC
Compound Name Medicarpin 3-O-glucoside
Kingdom Organic compounds
Prediction Hob Swissadme 1.0
Exact Mass 432.142
Formal Charge 0.0
Monoisotopic Mass 432.142
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 432.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -3.053786612903226
Inchi InChI=1S/C22H24O9/c1-27-10-2-4-12-14-9-28-15-7-11(3-5-13(15)21(14)30-16(12)6-10)29-22-20(26)19(25)18(24)17(8-23)31-22/h2-7,14,17-26H,8-9H2,1H3/t14-,17+,18+,19-,20+,21-,22+/m0/s1
Smiles COC1=CC2=C(C=C1)[C@@H]3COC4=C([C@@H]3O2)C=CC(=C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O
Nring 5.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Pterocarpans
Np Classifier Superclass Isoflavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Aconitum Orientale (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Ceanothus Integerrimus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Medicago Sativa (Plant) Rel Props:Reference:https://doi.org/10.2174/0929867033456729
  • 4. Outgoing r'ship FOUND_IN to/from Ononis Spinosa (Plant) Rel Props:Source_db:npass_chem_all