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Benzyl Isothiocyanate

PubChem CID: 2346

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Compound Synonyms benzyl isothiocyanate, 622-78-6, Benzylisothiocyanate, (Isothiocyanatomethyl)benzene, Benzylsenfoel, Tromacaps, Tromalyt, Urogran, Isothiocyanic acid, benzyl ester, Benzene, (isothiocyanatomethyl)-, Benzyl-isothiocyanate, isothiocyanatomethylbenzene, Isothiocyanic Acid Benzyl Ester, alpha-isothiocyanatotoluene, phenylmethyl isothiocyanate, Isothiocyanotaomethylbenzene, PMITC cpd, BITC, MFCD00004819, Toluene, alpha-isothiocyanato-, Benzylsenfoel [German], AB 2 (VAN), CCRIS 3145, NSC 118976, Isothiocyanatomethyl)benzene, isothiocyanatomethyl-benzene, EINECS 210-753-9, UNII-871J6YOR8Q, BRN 0386135, 1-(isothiocyanatomethyl)benzene, 871J6YOR8Q, AB 2, DTXSID0020155, CHEBI:17484, AI3-02736, NSC118976, NSC-118976, (isothiocyanatomethyl)-benzene, CHEMBL55285, DTXCID60155, FEMA NO. 4428, Toluene, .alpha.-isothiocyanato-, 4-12-00-02276 (Beilstein Handbook Reference), Benzylsenfoel (german), BENZYL ISOTHIOCYANATE (MART.), BENZYL ISOTHIOCYANATE [MART.], SR-05000002381, Tromocaps, benzene isothiocyanate, Benzyl isothio cyanate, Spectrum_001820, SpecPlus_000684, Tromalyt active substance, Spectrum2_000852, Spectrum3_000793, Spectrum4_001059, Spectrum5_001837, WLN: SCN1R, NCIMech_000859, alpha-Isothiocyanato-Toluene, isothiocyanato-methyl-benzene, Benzyl isothiocyanate, 98%, SCHEMBL44145, BSPBio_002526, KBioGR_001358, KBioSS_002323, DivK1c_006780, SPECTRUM1503006, SPBio_000863, (Isothiocyanatomethyl)benzene #, BITC, 17, Toluene, alpha -isothiocyanato-, KBio1_001724, KBio2_002321, KBio2_004889, KBio2_007457, KBio3_001746, Benzyl isothiocyanate, 98%, FG, HMS1921P18, Pharmakon1600-01503006, (Isothiocyanatomethyl)benzene, 9CI, BENZYL ISOTHIOCYANATE [FHFI], Tox21_201191, BBL013129, BDBM50240520, BENZYLISOTHIOCYANATE [WHO-DD], CCG-35868, NSC758206, s4783, STK399787, AKOS000212138, NSC-758206, PB43176, SDCCGMLS-0066697.P001, QTL1_000013, NCGC00094982-01, NCGC00094982-02, NCGC00094982-03, NCGC00094982-04, NCGC00258743-01, Benzyl isothiocyanate, analytical standard, BP-12924, CAS-622-78-6, HY-77813, NCI60_000455, PS-10308, SY010809, SBI-0052749.P002, DB-022613, CS-0006958, I0224, NS00011736, EN300-17059, C03098, F16583, AB00053249_03, SR-05000002381-1, SR-05000002381-2, BRD-K80253852-001-04-4, Q18341725, Z56869309, F0001-1663, 210-753-9
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 44.5
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCCCC1
Deep Smiles S=C=NCcccccc6
Heavy Atom Count 10.0
Classyfire Class Benzene and substituted derivatives
Description Benzyl isothiocyanate, also known as alpha-isothiocyanatotoluene or isothiocyanic acid, benzyl ester, belongs to benzene and substituted derivatives class of compounds. Those are aromatic compounds containing one monocyclic ring system consisting of benzene. Benzyl isothiocyanate is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Benzyl isothiocyanate is a mild, dusty, and horseradish tasting compound and can be found in a number of food items such as cabbage, garden onion, garden cress, and papaya, which makes benzyl isothiocyanate a potential biomarker for the consumption of these food products. Benzyl isothiocyanate (BITC) is an isothiocyanate found in plants of the mustard family .
Scaffold Graph Node Level C1CCCCC1
Isotope Atom Count 0.0
Molecular Complexity 132.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id Q9Y2Q3, P10649, O75762, P51450, P00352, P15428, P08684, P11473, O94782, P00176, P08183, Q9NPD5, Q9Y6L6, P14174, Q8NER1, n.a., P09467, Q93008, Q7BGE6, P0DTD1, P07858, P10275, Q16236, P04792, Q03181, P05412
Iupac Name isothiocyanatomethylbenzene
Prediction Hob 1.0
Class Benzene and substituted derivatives
Veber Rule True
Classyfire Superclass Benzenoids
Target Id NPT346, NPT94, NPT151, NPT109, NPT1250, NPT472
Xlogp 3.2
Superclass Benzenoids
Gsk 4 400 Rule True
Molecular Formula C8H7NS
Scaffold Graph Node Bond Level c1ccccc1
Prediction Swissadme 0.0
Inchi Key MDKCFLQDBWCQCV-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.125
Logs -2.904
Rotatable Bond Count 2.0
State Solid
Logd 2.516
Synonyms alpha-Isothiocyanatotoluene, Benzylsenfoel, Isothiocyanic acid, benzyl ester, a-Isothiocyanatotoluene, Α-isothiocyanatotoluene, Isothiocyanate, benzyl ester, Benzyl isothiocyanic acid, (Isothiocyanatomethyl)-benzene, (Isothiocyanatomethyl)benzene, (Isothiocyanatomethyl)benzene, 9ci, AB 2, alpha-Isothiocyanato-toluene, Benzyl isothio cyanate, Benzyl mustard oil, Benzyl-isothiocyanate, Benzylisothiocyanate, Isothiocyanato-methyl-benzene, Isothiocyanic acid benzyl ester, Isothiocyanotaomethylbenzene, Phenylmethyl isothiocyanate, Pmitc CPD, Tromacaps, Tromalyt, Tromalyt active substance, Tromocaps, Urogran, 3-Benzylisothiocyanic acid, 3-benzylisothiocyanate, benzyl isothiocyanate, benzyl-isothiocyanate, benzylisothiocyanate
Esol Class Soluble
Functional Groups CN=C=S
Compound Name Benzyl Isothiocyanate
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 149.03
Formal Charge 0.0
Monoisotopic Mass 149.03
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 149.21
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic homomonocyclic compounds
Lipinski Rule Of 5 True
Esol -3.0679516
Inchi InChI=1S/C8H7NS/c10-7-9-6-8-4-2-1-3-5-8/h1-5H,6H2
Smiles C1=CC=C(C=C1)CN=C=S
Nring 1.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Benzene and substituted derivatives

  • 1. Outgoing r'ship FOUND_IN to/from Allamanda Cathartica (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2000.9699526
  • 2. Outgoing r'ship FOUND_IN to/from Alliaria Petiolata (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 3. Outgoing r'ship FOUND_IN to/from Allium Cepa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Armoracia Rusticana (Plant) Rel Props:Source_db:fooddb_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Brassica Juncea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Brassica Oleracea (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.1530
  • 7. Outgoing r'ship FOUND_IN to/from Brassica Rapa (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.1335
  • 8. Outgoing r'ship FOUND_IN to/from Carica Papaya (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Carissa Carandas (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2004.9698764
  • 10. Outgoing r'ship FOUND_IN to/from Cascabela Thevetia (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2000.9699526
  • 11. Outgoing r'ship FOUND_IN to/from Descurainia Sophia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Lepidium Apetalum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 13. Outgoing r'ship FOUND_IN to/from Lepidium Didymum (Plant) Rel Props:Reference:ISBN:9788172362133
  • 14. Outgoing r'ship FOUND_IN to/from Lepidium Latifolium (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2006.9699401
  • 15. Outgoing r'ship FOUND_IN to/from Lepidium Sativum (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 16. Outgoing r'ship FOUND_IN to/from Moringa Oleifera (Plant) Rel Props:Reference:ISBN:9788172363130
  • 17. Outgoing r'ship FOUND_IN to/from Moringa Pterygosperma (Plant) Rel Props:Reference:ISBN:9780387706375
  • 18. Outgoing r'ship FOUND_IN to/from Raphanus Raphanistrum (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2005.9698955
  • 19. Outgoing r'ship FOUND_IN to/from Salvadora Oleoides (Plant) Rel Props:Reference:ISBN:9780387706375; ISBN:9788185042053
  • 20. Outgoing r'ship FOUND_IN to/from Salvadora Persica (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2002.9699795
  • 21. Outgoing r'ship FOUND_IN to/from Tropaeolum Majus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all