D-Glutamic Acid
PubChem CID: 23327
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| Compound Synonyms | D-glutamic acid, 6893-26-1, H-D-Glu-OH, (R)-2-aminopentanedioic acid, (2R)-2-aminopentanedioic acid, D-Glu, D-glutamate, Glutamic acid D-form, D-2-Aminopentanedioic acid, D-Glutaminsaeure, R-(-)-Glutamic acid, Glutamic acid, D-, D-(-)-Glutamic acid, D-Glutaminic acid, MFCD00063112, DTXSID1048675, CHEBI:15966, Tocris-0217, D-2-Aminoglutaric acid, Q479989WEA, EINECS 230-000-8, Lopac-G-2128, NSC 77686, CHEMBL76232, AI3-09072, 138-16-9, DTXCID1028601, GLUTAMIC ACID D-FORM [MI], C5H9NO4, glutamate, NSC-77686, DGL, Gamma-D-Glutamic Acid, NCGC00024501-02, (2R)-2-aminopentanedioate, L(+)-Glutamic acid, delta-Glutamate, (r)-1-aminopropane-1,3-dicarboxylic acid, UNII-Q479989WEA, gammaDPGA, delta-Glutaminate, Glutamic acid #, R()Glutamic acid, 2-deoxy-d-glu, (r)-glutamic acid, delta-Glutamic acid, delta-Glutaminsaeure, Glutamic acid Dform, D-2-Aminoglutarate, R-(-)-Glutamate, delta-Glutaminic acid, Lopac-gamma-2128, delta-2-Aminoglutarate, D-2-Aminopentanedioate, D2Aminopentanedioic acid, (R)-2-aminopentanedioate, delta-2-Aminopentanedioate, Biomol-NT_000169, delta-2-Aminoglutaric acid, (R)-2-Aminoglutaric acid, D-[14C]Glu, (R)-2-aminopentanedioicacid, D-Glutamic acid, >=99%, SCHEMBL43222, delta-2-Aminopentanedioic acid, BPBio1_001130, GTPL4708, BDBM26431, CHEBI:53375, D-Glutamic acid, >=99% (TLC), Tox21_113052, HB0243, PDSP1_000131, PDSP1_001486, PDSP2_000130, PDSP2_001470, AKOS015854118, CS-6255, DB02517, FG02337, NCGC00015470-01, NCGC00024501-01, NCGC00024501-03, NCGC00024501-04, AC-15064, AC-24113, AS-12791, CAS-6893-26-1, HY-100805, (2R)-2-azaniumyl-5-hydroxy-5-oxopentanoate, (R)-1-Aminopropane-1,3-dicarboxylic acid, G0057, NS00068393, EN300-78764, R-(-)-1-Aminopropane-1,3-dicarboxylic acid, C00217, M02964, SR-01000597732, D-Glutamic acid, Vetec(TM) reagent grade, >=99%, SR-01000597732-1, Q27077040, Z1741982700, 230-000-8 |
|---|---|
| Topological Polar Surface Area | 101.0 |
| Hydrogen Bond Donor Count | 3.0 |
| Heavy Atom Count | 10.0 |
| Description | There are two forms of glutamic acid found in nature: L-glutamic acid and D-glutamic acid. D-glutamic acid, is not endogenously produced in higher mammals. It is found naturally primarily in the cell walls of certain bacteria. D-glutamate is also present in certain foods e.g., soybeans and also arises from the turnover of the intestinal tract microflora, whose cell walls contain significant D-glutamate. Unlike other D-amino acids, D-glutamate is not oxidized by the D-amino acid oxidases, and therefore this detoxification pathway is not available for handling D-glutamate. Likewise, D-glutamic acid, when ingested, largely escapes most deamination reactions (unlike the L-counterpart). Free D-glutamate is found in mammalian tissue at surprisingly high levels, with D-glutamate accounting for 9% of the total glutamate present in liver. D-glutamate is the most potent natural inhibitor of glutathione synthesis identified to date and this may account for its localization to the liver, since circulating D-glutamate may alter redox stabiity (PMID 11158923). Certain eels are known to use D-glutamic acid as a phermone for chemical communication. [HMDB] |
| Isotope Atom Count | 0.0 |
| Molecular Complexity | 145.0 |
| Database Name | cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;npass_chem_all;pubchem |
| Defined Atom Stereocenter Count | 1.0 |
| Uniprot Id | Q9UI32, O94925, P23385, P31421, P31422, P31423, P31424, P35349, P35400, Q13255, Q14416, O15303, Q03469, Q63273, P19490, P56068, Q836J0, Q9F4F7, P14618, P15917, P08482, P08684, P10635, P05177, O94782, Q9C0B1, Q9NUW8, P27695, P9WPW9, P00915, P00918, Q4CVY4, P10275 |
| Iupac Name | (2R)-2-aminopentanedioic acid |
| Prediction Hob | 1.0 |
| Class | Carboxylic acids and derivatives |
| Target Id | NPT52, NPT109, NPT110, NPT208 |
| Xlogp | -3.7 |
| Superclass | Organic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Molecular Formula | C5H9NO4 |
| Prediction Swissadme | 0.0 |
| Inchi Key | WHUUTDBJXJRKMK-GSVOUGTGSA-N |
| Fcsp3 | 0.6 |
| Logs | -1.092 |
| Rotatable Bond Count | 4.0 |
| State | Solid |
| Logd | -0.644 |
| Synonyms | (2R)-2-aminopentanedioate, (2R)-2-aminopentanedioic acid, (R)-2-aminopentanedioate, (R)-2-aminopentanedioic acid, D-2-Aminoglutarate, D-2-Aminoglutaric acid, D-2-Aminopentanedioate, D-2-Aminopentanedioic acid, D-Glutamate, D-Glutamic acid, D-Glutaminate, D-Glutaminic acid, D-Glutaminsaeure, delta-2-Aminoglutarate, delta-2-Aminoglutaric acid, delta-2-Aminopentanedioate, delta-2-Aminopentanedioic acid, delta-Glutamate, delta-Glutamic acid, delta-Glutaminate, delta-Glutaminic acid, delta-Glutaminsaeure, DGL, glutamic acid D-form, Lopac-G-2128, Lopac-gamma-2128, R-(-)-Glutamate, R-(-)-Glutamic acid, Tocris-0217, (R)-2-Aminopentanedioic acid, Glutamic acid D-form, (R)-2-Aminopentanedioate, Glutamate D-form, (2R)-2-Aminopentanedioate, (2R)-2-Aminopentanedioic acid, Glutamate, Lopac-g-2128, Glutamic acid, (D)-isomer, L Glutamic acid, L-Glutamate, L-Glutamic acid, D Glutamate, Glutamate, potassium, L-Glutamate, aluminum, Aluminum L glutamate, Glutamic acid, L Glutamate, Aluminum L-glutamate, Potassium glutamate |
| Compound Name | D-Glutamic Acid |
| Kingdom | Organic compounds |
| Prediction Hob Swissadme | 0.0 |
| Exact Mass | 147.053 |
| Formal Charge | 0.0 |
| Monoisotopic Mass | 147.053 |
| Hydrogen Bond Acceptor Count | 5.0 |
| Molecular Weight | 147.13 |
| Covalent Unit Count | 1.0 |
| Total Atom Stereocenter Count | 1.0 |
| Total Bond Stereocenter Count | 0.0 |
| Molecular Framework | Aliphatic acyclic compounds |
| Esol | 1.8364940000000003 |
| Inchi | InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1 |
| Smiles | C(CC(=O)O)[C@H](C(=O)O)N |
| Nring | 0.0 |
| Defined Bond Stereocenter Count | 0.0 |
| Taxonomy Direct Parent | Glutamic acid and derivatives |
- 1. Outgoing r'ship
FOUND_INto/from Achyranthes Bidentata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 2. Outgoing r'ship
FOUND_INto/from Achyranthes Fauriei (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 3. Outgoing r'ship
FOUND_INto/from Achyranthes Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 4. Outgoing r'ship
FOUND_INto/from Acorus Gramineus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 5. Outgoing r'ship
FOUND_INto/from Acorus Tatarinowii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 6. Outgoing r'ship
FOUND_INto/from Allium Sativum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 7. Outgoing r'ship
FOUND_INto/from Brassica Juncea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 8. Outgoing r'ship
FOUND_INto/from Ginkgo Biloba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 9. Outgoing r'ship
FOUND_INto/from Sinapis Alba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 10. Outgoing r'ship
FOUND_INto/from Tussilago Farfara (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all