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17alpha-hydroxywithanolide D

PubChem CID: 23266161

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Compound Synonyms 17alpha-hydroxywithanolide D, CHEBI:66329, 4beta,17alpha,20alpha-trihydroxy-1-oxo-5beta,6beta-epoxy-20S,22R-witha-2,24-dienolide, (1S,2R,6S,7R,9R,11S,12S,15R,16S)-15-[(1S)-1-[(2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl]-1-hydroxyethyl]-6,15-dihydroxy-2,16-dimethyl-8-oxapentacyclo[9.7.0.02,7.07,9.012,16]octadec-4-en-3-one, (4beta,5beta,6beta,22R)-4,17,20-Trihydroxy-5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione, (1S,2R,6S,7R,9R,11S,12S,15R,16S)-15-((1S)-1-((2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl)-1-hydroxyethyl)-6,15-dihydroxy-2,16-dimethyl-8-oxapentacyclo(9.7.0.02,7.07,9.012,16)octadec-4-en-3-one, Q27134877
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 117.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCCC(CC2CCC3C2CCC2C3CC3CC34CCCC(C)C24)C1
Np Classifier Class Ergostane steroids
Deep Smiles CC=CC)C=O)O[C@H]C6)[C@@][C@@]O)CC[C@@H][C@]5C)CC[C@H][C@H]6C[C@@H][C@][C@]6C)C=O)C=C[C@@H]6O))))))O3)))))))))))))O)C
Heavy Atom Count 35.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level OC1CCCC(CC2CCC3C2CCC2C3CC3OC34CCCC(O)C24)O1
Classyfire Subclass Steroid lactones
Isotope Atom Count 0.0
Molecular Complexity 1080.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 11.0
Iupac Name (1S,2R,6S,7R,9R,11S,12S,15R,16S)-15-[(1S)-1-[(2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl]-1-hydroxyethyl]-6,15-dihydroxy-2,16-dimethyl-8-oxapentacyclo[9.7.0.02,7.07,9.012,16]octadec-4-en-3-one
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 1.7
Gsk 4 400 Rule False
Molecular Formula C28H38O7
Scaffold Graph Node Bond Level O=C1C=CCC(CC2CCC3C2CCC2C3CC3OC34CC=CC(=O)C24)O1
Prediction Swissadme 1.0
Inchi Key JVEUOKCSZLCPOI-IBELMYMKSA-N
Silicos It Class Soluble
Fcsp3 0.7857142857142857
Logs -4.5
Rotatable Bond Count 2.0
Logd 2.981
Synonyms 17 alpha-hydroxywithanolide d, 17-hydroxywithanolide-d
Esol Class Soluble
Functional Groups CC1=C(C)C(=O)OCC1, CC=CC(C)=O, CO, C[C@H]1O[C@@]1(C)C
Compound Name 17alpha-hydroxywithanolide D
Prediction Hob Swissadme 0.0
Exact Mass 486.262
Formal Charge 0.0
Monoisotopic Mass 486.262
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 486.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 11.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.7896510000000014
Inchi InChI=1S/C28H38O7/c1-14-12-21(34-23(31)15(14)2)26(5,32)27(33)11-9-17-16-13-22-28(35-22)20(30)7-6-19(29)25(28,4)18(16)8-10-24(17,27)3/h6-7,16-18,20-22,30,32-33H,8-13H2,1-5H3/t16-,17-,18-,20-,21+,22+,24-,25-,26-,27+,28+/m0/s1
Smiles CC1=C(C(=O)O[C@H](C1)[C@@](C)([C@]2(CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3C[C@@H]5[C@]6([C@@]4(C(=O)C=C[C@@H]6O)C)O5)C)O)O)C
Nring 6.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Steroids

  • 1. Outgoing r'ship FOUND_IN to/from Tubocapsicum Anomalum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Withania Somnifera (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all