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Santonin

PubChem CID: 221071

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Compound Synonyms santonin, alpha-Santonin, 481-06-1, (-)-alpha-Santonin, Semenen, Santoninum, Santoninic anhydride, L-alpha-Santonin, (-)-Santonine, (-)-Santonin, UNII-1VL8J38ERO, NSC 4900, NSC-4900, 1VL8J38ERO, DTXSID7045312, CHEBI:16363, NSC4900, EINECS 207-560-7, MFCD00135865, NSC 41311, (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-3a,4,5,9b-tetrahydro-3H-benzo[g][1]benzofuran-2,8-dione, AI3-19471, DTXCID5025312, .alpha.-Santonin, (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-3a,5,5a,9b-tetrahydronaphtho[1,2-b]furan-2,8(3H,4H)-dione, SANTONIN (MART.), SANTONIN [MART.], 11-Epiisoeusantona-1,4-dienic acid, 6alpha-hydroxy-3-oxo-, gamma-lactone, (3S)-2,3,3a,4,5,5a,8,9bbeta-Octahydro-3,5abeta,9-trimethylnaphtho(1,2-b)furan-2,8-dion, (3S,5aS,9bS)-3a,5,5a,9b-Tetrahydro-3,5a,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)dione, Eudesma-1,4-dien-12-oic acid, 6-alpha-hydroxy-3-oxo-, gamma-lactone, (11S)-(-)-, Naphtho(1,2-b)puran-2,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, C15H14O3, 6alpha-hydroxy-3-oxo-11-epiisoeusantona-1,4-dienic acid gamma-lactone, l-.alpha.-Santonin, (11S)-6alpha-hydroxy-3-oxoeudesma-1,4-dien-12-oic acid gamma-lactone, (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-3a,4,5,9b-tetrahydro-3H-benzo[g]benzofuran-2,8-dione, Eudesma-1,4-dien-12-oic acid, 6-alpha-hydroxy-3-oxo-, gamma-lactone, (11S)-, Santonin [JAN], (3S,3AS,5AS)-3,5A,9-TRIMETHYL-3A,4,5,5A-TETRAHYDRONAPHTHO(1,2-B)FURAN-2,8(3H,9BH)-DIONE, (3S,3AS,5AS,9BS)-3A,5,5A,9B-TETRAHYDRO-3,5A,9-TRIMETHYLNAPHTHO(1,2-B)FURAN-2,8(3H,4H)-DIONE, naphtho[1,2-b]furan-2,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, (3S,3aS,5aS,9bS)-, (-)-.alpha.-Santonin, Santonin [JAN:NF], SR-01000635568, santonins, Santonin-a, NCGC00016461-01, Santonin (TN), (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-3a,5,5a,9b-tetrahydronaphtho(1,2-b)furan-2,8(3H,4H)-dione, (3S,3aS,5aS,9bS)-3a,5,5a,9b-Tetrahydro-3,5a,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione, CAS-481-06-1, Naphtho(1,2-b)furan-2,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, (3S,3aS,5aS,9bS)-, ()-alpha-Santonin, Santonin (Standard), SANTONINE, Santonin (JP18), Spectrum_000790, SpecPlus_000318, (-)- alpha -Santonin, Prestwick0_001070, Prestwick1_001070, Prestwick2_001070, Prestwick3_001070, Spectrum2_000699, Spectrum3_001245, Spectrum4_001476, Spectrum5_000151, SANTONINUM [HPUS], SANTONIN [WHO-DD], UPCMLD-DP084, BSPBio_001060, BSPBio_002750, KBioGR_002051, KBioSS_001270, SPECTRUM300542, MLS002154141, Naphtho(1,2-b)furan-2,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, (3S-(3alpha,3aalpha,5abeta,9bbeta))-, DivK1c_006414, SPBio_000857, SPBio_002970, alpha-Santonin, (-)-Santonin, BPBio1_001166, CHEMBL259254, MEGxp0_001636, SCHEMBL1133565, .ALPHA.-SANTONIN [MI], UPCMLD-DP084:001, CHEBI:26604, GTPL12448, HY-B1761R, KBio1_001358, KBio2_001270, KBio2_003838, KBio2_006406, KBio3_002250, (-)-alpha-Santonin, >=99%, XJHDMGJURBVLLE-BOCCBSBMSA-N, HMS1571E22, HMS2098E22, HMS2268H12, (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-3a,4,5,5a-tetrahydronaphtho[1,2-b]furan-2,8(3H,9bH)-dione, HY-B1761, Tox21_110445, CCG-40021, s3999, AKOS015895177, Tox21_110445_1, FS65157, LMPR0103190001, SDCCGMLS-0066491.P001, (-)-alpha-Santonin, analytical standard, NCGC00161640-01, NCGC00161640-02, NCGC00161640-03, NCGC00263447-01, SMR000112520, AB00376930, CS-0013789, NS00022216, S0521, EN300-34530, C02206, D00154, WLN: T B566 COV LV IHTT&J E1 I1 M1, A827469, AC-907/21098009, AJ-738/21061005, AK-861/20800026, Q413166, SR-01000635568-1, SR-01000635568-4, SR-01000635568-5, BRD-K58787433-001-05-4, BRD-K58787433-001-08-8, BRD-K58787433-001-12-0, Santonin, European Pharmacopoeia (EP) Reference Standard, Z359371114, 11-Epiisoeusantona-1, 6.alpha.-hydroxy-3-oxo-, .gamma.-lactone, Eudesma-1, 6.alpha.-hydroxy-3-oxo-, .gamma.-lactone, (11S)-, Eudesma-1, 6.alpha.-hydroxy-3-oxo-, .gamma.-lactone, (11S)-(-)-, Naphtho[1,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, 3a,5,5a,9b-Tetrahydro-3,5a,9-trimethyl-naphtho[1,2-b]puran-2,8(3H,4H)-dione, (3S,3aS,5aS,9bS)-2,3,3a,4,5,5a,8,9b-Octahydro-3,5a,9-trimethylnaphtho(1,2-b)furan-2,8-dione, (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-2H,3H,3aH,4H,5H,5aH,8H,9bH-naphtho[1,2-b]furan-2,8-dione, 1,3,4,4a,7-Hexahydro-1-hydroxy-.alpha., 4a,8-trimethyl-7-oxo-2-naphthaleneacetic acid .gamma.-lactone, 207-560-7, InChI=1/C15H18O3/c1-8-10-4-6-15(3)7-5-11(16)9(2)12(15)13(10)18-14(8)17/h5,7-8,10,13H,4,6H2,1-3H3/t8-,10-,13-,15-/m0/s, Naphtho[1,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, [3S-(3.alpha.,3a.alpha.,5a.beta.,9b.beta.)]-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 43.4
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2CCC3CC(C)CC3C2C1
Np Classifier Class Eudesmane sesquiterpenoids
Deep Smiles C[C@@H]C=O)O[C@H][C@H]5CC[C@@]C6=CC)C=O)C=C6)))))C
Heavy Atom Count 18.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level OC1CCC2CCC3CC(O)OC3C2C1
Classyfire Subclass Terpene lactones
Isotope Atom Count 0.0
Molecular Complexity 500.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 4.0
Uniprot Id n.a., P04150, O75496, O42275, P81908, Q9Y6L6, Q9NPD5, P01375
Iupac Name (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-3a,4,5,9b-tetrahydro-3H-benzo[g][1]benzofuran-2,8-dione
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 2.3
Gsk 4 400 Rule True
Molecular Formula C15H18O3
Scaffold Graph Node Bond Level O=C1C=CC2CCC3CC(=O)OC3C2=C1
Prediction Swissadme 0.0
Inchi Key XJHDMGJURBVLLE-BOCCBSBMSA-N
Silicos It Class Soluble
Fcsp3 0.6
Logs -2.846
Rotatable Bond Count 0.0
Logd 2.013
Synonyms alpha-santonin, santonin, α-santonin
Esol Class Soluble
Functional Groups CC1=C(C)CC=CC1=O, COC(C)=O
Compound Name Santonin
Prediction Hob Swissadme 0.0
Exact Mass 246.126
Formal Charge 0.0
Monoisotopic Mass 246.126
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 246.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.8097972
Inchi InChI=1S/C15H18O3/c1-8-10-4-6-15(3)7-5-11(16)9(2)12(15)13(10)18-14(8)17/h5,7-8,10,13H,4,6H2,1-3H3/t8-,10-,13-,15-/m0/s1
Smiles C[C@H]1[C@@H]2CC[C@]3(C=CC(=O)C(=C3[C@H]2OC1=O)C)C
Nring 3.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Sesquiterpenoids

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