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Euphornin B

PubChem CID: 21771753

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Compound Synonyms euphornin B, ((1S,2S,3aR,4S,5S,6E,9R,11R,12E,13aS)-4,11-diacetyloxy-3a,9-dihydroxy-2,5,8,8,12-pentamethyl-2,3,4,5,9,10,11,13a-octahydro-1H-cyclopenta(12)annulen-1-yl) benzoate, (1R,2S,3AS,4R,5S,9S,11R,13as)-4,11-bis(acetyloxy)-3a,9-dihydroxy-2,5,8,8,12-pentamethyl-1H,2H,3H,3ah,4H,5H,8H,9H,10H,11H,13ah-cyclopenta(12)annulen-1-yl benzoic acid, (1R,2S,3AS,4R,5S,9S,11R,13as)-4,11-bis(acetyloxy)-3a,9-dihydroxy-2,5,8,8,12-pentamethyl-1H,2H,3H,3ah,4H,5H,8H,9H,10H,11H,13ah-cyclopenta[12]annulen-1-yl benzoic acid, [(1S,2S,3aR,4S,5S,6E,9R,11R,12E,13aS)-4,11-diacetyloxy-3a,9-dihydroxy-2,5,8,8,12-pentamethyl-2,3,4,5,9,10,11,13a-octahydro-1H-cyclopenta[12]annulen-1-yl] benzoate, CHEMBL463643, 90052-87-2
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 119.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CC1CCC2CCCCCCCCCCC21)C1CCCCC1
Np Classifier Class Jatrophane diterpenoids
Deep Smiles CC=O)O[C@H][C@@H]C)/C=C/CC)C)[C@H]O)C[C@H]/C=C/[C@@H][C@]%12O)C[C@@H][C@@H]5OC=O)cccccc6)))))))))C))))))/C))OC=O)C
Heavy Atom Count 39.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level OC(OC1CCC2CCCCCCCCCCC21)C1CCCCC1
Classyfire Subclass Diterpenoids
Isotope Atom Count 0.0
Molecular Complexity 962.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name [(1S,2S,3aR,4S,5S,6E,9R,11R,12E,13aS)-4,11-diacetyloxy-3a,9-dihydroxy-2,5,8,8,12-pentamethyl-2,3,4,5,9,10,11,13a-octahydro-1H-cyclopenta[12]annulen-1-yl] benzoate
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 4.6
Gsk 4 400 Rule False
Molecular Formula C31H42O8
Scaffold Graph Node Bond Level O=C(OC1CCC2CCC=CCCCCC=CC21)c1ccccc1
Prediction Swissadme 0.0
Inchi Key STETZDTWJFKIHV-OWVGVDTNSA-N
Silicos It Class Moderately soluble
Fcsp3 0.5806451612903226
Logs -4.617
Rotatable Bond Count 7.0
Logd 2.605
Synonyms euphornin b
Esol Class Moderately soluble
Functional Groups C/C(C)=CC, C/C=C/C, CC(=O)OC, CO, cC(=O)OC
Compound Name Euphornin B
Prediction Hob Swissadme 0.0
Exact Mass 542.288
Formal Charge 0.0
Monoisotopic Mass 542.288
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 542.7
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 2.0
Lipinski Rule Of 5 True
Esol -5.735493953846156
Inchi InChI=1S/C31H42O8/c1-18-13-14-30(6,7)26(34)16-25(37-21(4)32)19(2)15-24-27(39-29(35)23-11-9-8-10-12-23)20(3)17-31(24,36)28(18)38-22(5)33/h8-15,18,20,24-28,34,36H,16-17H2,1-7H3/b14-13+,19-15+/t18-,20-,24-,25+,26+,27-,28-,31+/m0/s1
Smiles C[C@H]1C[C@]2([C@H]([C@H]1OC(=O)C3=CC=CC=C3)/C=C(/[C@@H](C[C@H](C(/C=C/[C@@H]([C@@H]2OC(=O)C)C)(C)C)O)OC(=O)C)\C)O
Nring 3.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 2.0
Egan Rule True
Np Classifier Superclass Diterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Euphorbia Helioscopia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all