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(1S,2R,5S,6S,7R,9R,11R,12R,15S,16S)-15-[(1S)-1-[(2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl]-1-hydroxyethyl]-6,12,15-trihydroxy-5-methoxy-2,16-dimethyl-8-oxapentacyclo[9.7.0.02,7.07,9.012,16]octadecan-3-one

PubChem CID: 21607601

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Compound Synonyms CHEMBL4472327
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 146.0
Hydrogen Bond Donor Count 4.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCCC(CC2CCC3C2CCC2C3CC3CC34CCCC(C)C24)C1
Np Classifier Class Ergostane steroids
Deep Smiles CO[C@H]CC=O)[C@][C@][C@H]6O))O[C@@H]3C[C@@H][C@@H]7CC[C@][C@@]6O)CC[C@@]5O)[C@][C@H]CC=CC=O)O6))C))C))))O)C))))))C))))))))))C
Heavy Atom Count 38.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level OC1CCCC(CC2CCC3C2CCC2C3CC3OC34CCCC(O)C24)O1
Classyfire Subclass Steroid lactones
Isotope Atom Count 0.0
Molecular Complexity 1140.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 12.0
Iupac Name (1S,2R,5S,6S,7R,9R,11R,12R,15S,16S)-15-[(1S)-1-[(2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl]-1-hydroxyethyl]-6,12,15-trihydroxy-5-methoxy-2,16-dimethyl-8-oxapentacyclo[9.7.0.02,7.07,9.012,16]octadecan-3-one
Prediction Hob 0.0
Veber Rule False
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 0.2
Gsk 4 400 Rule False
Molecular Formula C29H42O9
Scaffold Graph Node Bond Level O=C1C=CCC(CC2CCC3C2CCC2C3CC3OC34CCCC(=O)C24)O1
Prediction Swissadme 0.0
Inchi Key SZFJLHBQKXQARU-XPHFJZSBSA-N
Silicos It Class Soluble
Fcsp3 0.8620689655172413
Logs -4.151
Rotatable Bond Count 3.0
Logd 0.727
Synonyms physalactone, physalactone (4β,17,20α(r)-trihydroxy-3-methoxy-l-oxo-5β,6β-epoxy-witha-8(14),24-dienolide)
Esol Class Soluble
Functional Groups CC(C)=O, CC1=C(C)C(=O)OCC1, CO, COC, C[C@H]1O[C@@]1(C)C
Compound Name (1S,2R,5S,6S,7R,9R,11R,12R,15S,16S)-15-[(1S)-1-[(2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl]-1-hydroxyethyl]-6,12,15-trihydroxy-5-methoxy-2,16-dimethyl-8-oxapentacyclo[9.7.0.02,7.07,9.012,16]octadecan-3-one
Prediction Hob Swissadme 0.0
Exact Mass 534.283
Formal Charge 0.0
Monoisotopic Mass 534.283
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 534.6
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 12.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.076505200000003
Inchi InChI=1S/C29H42O9/c1-14-11-20(37-23(32)15(14)2)26(5,33)28(35)10-9-27(34)17-12-21-29(38-21)22(31)18(36-6)13-19(30)25(29,4)16(17)7-8-24(27,28)3/h16-18,20-22,31,33-35H,7-13H2,1-6H3/t16-,17+,18-,20+,21+,22-,24-,25-,26-,27+,28-,29-/m0/s1
Smiles CC1=C(C(=O)O[C@H](C1)[C@@](C)([C@@]2(CC[C@@]3([C@@]2(CC[C@H]4[C@H]3C[C@@H]5[C@]6([C@@]4(C(=O)C[C@@H]([C@@H]6O)OC)C)O5)C)O)O)O)C
Nring 6.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Steroids

  • 1. Outgoing r'ship FOUND_IN to/from Physalis Alkekengi (Plant) Rel Props:Reference:ISBN:9788172361150
  • 2. Outgoing r'ship FOUND_IN to/from Physalis Peruviana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all