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Icariside E4

PubChem CID: 21589939

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Compound Synonyms Icariside E4, 126253-42-7, CHEBI:68965, (2S,3R,4R,5R,6S)-2-[4-[(2R,3S)-3-(hydroxymethyl)-5-(3-hydroxypropyl)-7-methoxy-2,3-dihydro-1-benzofuran-2-yl]-2-methoxyphenoxy]-6-methyloxane-3,4,5-triol, alpha-L-Mannopyranoside, 4-[(2R,3S)-2,3-dihydro-3-(hydroxymethyl)-5-(3-hydroxypropyl)-7-methoxy-2-benzofuranyl]-2-methoxyphenyl 6-deoxy-, CHEMBL1923075, DTXSID101317861, HY-N9854, AKOS040762654, (2R,3S)-2-(3-Methoxy-4-beta-D-rhamnopyranosyloxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-7-methoxybenzofuran-5-propan-1-ol, DA-64357, CS-0203989, Q27137317
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 147.0
Hydrogen Bond Donor Count 5.0
Pfizer 3 75 Rule True
Scaffold Graph Level C1CCC(CC2CCC(C3CC4CCCCC4C3)CC2)CC1
Np Classifier Class Neolignans
Deep Smiles OCCCccc[C@@H]CO))[C@@H]Oc5cc9)OC)))))cccccc6)OC)))O[C@@H]O[C@@H]C)[C@@H][C@H][C@H]6O))O))O
Heavy Atom Count 36.0
Classyfire Class 2-arylbenzofuran flavonoids
Scaffold Graph Node Level C1CCC(OC2CCC(C3CC4CCCCC4O3)CC2)OC1
Isotope Atom Count 0.0
Molecular Complexity 681.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 7.0
Iupac Name (2S,3R,4R,5R,6S)-2-[4-[(2R,3S)-3-(hydroxymethyl)-5-(3-hydroxypropyl)-7-methoxy-2,3-dihydro-1-benzofuran-2-yl]-2-methoxyphenoxy]-6-methyloxane-3,4,5-triol
Prediction Hob 0.0
Veber Rule False
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 0.8
Gsk 4 400 Rule False
Molecular Formula C26H34O10
Scaffold Graph Node Bond Level c1ccc2c(c1)CC(c1ccc(OC3CCCCO3)cc1)O2
Prediction Swissadme 0.0
Inchi Key FYWCDZKQBWSMDD-YGYBHAICSA-N
Silicos It Class Soluble
Fcsp3 0.5384615384615384
Logs -4.253
Rotatable Bond Count 9.0
Logd 1.345
Synonyms icariside e4
Esol Class Soluble
Functional Groups CO, cOC, cO[C@@H](C)OC
Compound Name Icariside E4
Prediction Hob Swissadme 0.0
Exact Mass 506.215
Formal Charge 0.0
Monoisotopic Mass 506.215
Hydrogen Bond Acceptor Count 10.0
Molecular Weight 506.5
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.124664266666669
Inchi InChI=1S/C26H34O10/c1-13-21(29)22(30)23(31)26(34-13)35-18-7-6-15(11-19(18)32-2)24-17(12-28)16-9-14(5-4-8-27)10-20(33-3)25(16)36-24/h6-7,9-11,13,17,21-24,26-31H,4-5,8,12H2,1-3H3/t13-,17+,21-,22+,23+,24-,26-/m0/s1
Smiles C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(C=C(C=C2)[C@H]3[C@@H](C4=C(O3)C(=CC(=C4)CCCO)OC)CO)OC)O)O)O
Nring 4.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Lignans

  • 1. Outgoing r'ship FOUND_IN to/from Acer Saccharum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Austrocedrus Chilensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Haloxylon Recurvum (Plant) Rel Props:Source_db:npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Nymphaea Odorata (Plant) Rel Props:Source_db:npass_chem_all